AI Progress & Market Landscape/reviewed 2026-08-08
How is AI advancing—and who is building it?
One signal is never enough. Scivity tracks frontier capability, the market stack that turns models into products, and the scientific systems pushing research toward autonomy—with control reported as a separate, lagging indicator.
Confidence band 73–81. The largest capability gaps are long-horizon reliability, AI-led R&D and robust action beyond digital environments.
Not a probability · not a countdown
The index
Six capability vectors. One moving frontier.
The score uses a weighted arithmetic mean of demonstrated frontier capabilities. It counts the model together with normal tools and agent scaffolding, while safety and control remain visible as a separate diagnostic instead of suppressing the capability score.
018622% weight
General reasoning
Frontier systems solve a broad range of expert cognitive tasks and transfer across domains, with remaining brittleness concentrated in genuinely novel or adversarial problems.
Top systems plan, browse, code, use computers and coordinate sub-agents across real workflows; agent scaffolding counts when it is part of normal deployment.
Multi-day production runs demonstrate meaningful endurance, while reliability and recovery from compounding errors still require supervision and verification.
Multimodal perception and computer use are useful across real digital environments. Physical embodiment remains evidence, not a prerequisite for cognitive AGI.
AI systems produce externally validated algorithms, vulnerabilities and scientific findings, although the strongest results still use structured search and verification loops.
Models already accelerate coding, evaluation and research inside frontier labs. Recursive autonomous self-improvement is not required for partial credit and has not been demonstrated.
This is a capability-proximity index, not a probability of AGI, a countdown or a claim that any single raw model has reached this level. Safety and control are reported separately so weak alignment does not erase observed capability progress. Each dimension is editorially scored from primary evidence and independent measurements; uncertainty is shown explicitly because no accepted operational definition of AGI exists.
Signal feed
What actually moved.
A curated frontier-news feed where every item answers one question: does this change what AI can do, how long it can do it, where it can run, or whether humans can still supervise it?
2026-07-30
Models
OpenAI cuts GPT-5.6 deployment costs weeks after launch
OpenAI reduced GPT-5.6 Luna pricing by 80% and Terra pricing by 20%, widening access to the same model family used for agentic knowledge work.
Why it matters: Capability diffusion depends on price as well as benchmark scores; cheaper inference moves frontier-class agents into more products and higher-volume workflows.
OpenAI models found and exploited a novel path outside their evaluation target
During a Hugging Face evaluation, a combination of GPT-5.6 Sol and a pre-release model discovered and exploited a real attack path without source-code access.
Why it matters: It is simultaneously a capability jump and a control warning: persistent agents can exceed the boundary designers thought they were testing.
Kimi K3 brings frontier-class capability to open weights
Moonshot AI released a 2.8T-parameter MoE model with 104B active parameters, native vision and a one-million-token context window; the full weights followed on July 27.
Why it matters: The frontier is no longer confined to closed US APIs, though self-hosting K3 remains a datacenter-scale job.
GPT-5.6 links frontier capability to parallel agents and internal AI R&D
The Sol, Terra and Luna family adds programmatic tool use and multi-agent execution. OpenAI reports a 16.2-point gain on its internal recursive-self-improvement evaluation bundle.
Why it matters: The strongest evidence for AI improving AI is now operational adoption inside a frontier lab, not a benchmark headline alone.
A production coding-agent mission reportedly ran for 16 days
Factory has described a longest recorded multi-agent software mission of 16 days. This is an agent-system result—not proof that one model reasoned continuously for 16 days, and not a Chinese-model claim.
Why it matters: Runtime endurance is becoming real, but it must be separated from independent model reliability and task difficulty.
Anthropic turns lower-cost agents into a reproducible science workbench
Claude Sonnet 5 moved stronger planning and tool use into Anthropic's lower-cost model tier, while Claude Science packaged multi-agent analysis, auditable artifacts, specialist tools and lab compute access into a dedicated research environment.
Why it matters: AI progress reaches science through usable systems, not raw model scores alone: cheaper agents plus reproducible artifacts make sustained research workflows accessible to more labs.
AlphaEvolve expands from algorithm records into science and infrastructure
DeepMind reports deployments across physics, neuroscience, cryptography, energy and neural-network optimization, with automatically evaluated discoveries.
Why it matters: Validated novelty is a stronger AGI signal than fluent answers: the system must produce something that survives an external check.
From chips and cloud capacity to models, agents, applications, robotics and control. The map covers every major market layer, while the directory uses a sourced anchor set instead of pretending to list every startup.
98 organizations13 layers6 regionsas of 2026-08-08
>90%
2025
Frontier models built by industry
Industry produced more than 90% of notable frontier models in 2025.
88%
2025
Organizations using AI
Reported organizational AI adoption reached 88%.
$285.9B
2025
U.S. private AI investment
U.S. private AI investment reached $285.9 billion in 2025.
≈66%
2026 report
Agent success on OSWorld
Agent success on OSWorld rose from 12% to roughly 66%, while failures remain material.
AI-native platform for next-generation protein characterization. Automates mass-spectrometry interpretation so biologic drug candidates can be characterized and quality-assessed faster.
AI-native protein characterization platformMass spectrometry analysis agentsProteoform analysis workflows
Public antibody-discovery platform company. Integrates single-cell screening, computation, antibody engineering, translational science, and clinical manufacturing from target to clinic.
Scope: Global organizations, platforms and products across the full AI value chain. Inclusion requires a material role in the value chain and a current primary source; layer membership is multi-select.
The AI-for-Science cohort keeps its deeper evidence, finance and benchmark ledgers below. General-market entities are not assigned science-specific scores.
Model atlas
What can run where.
Not another leaderboard. This is the practical layer: which frontier family is suited to what work, whether the weights exist, how large it is, and whether you can run it locally or only through a provider.
OpenAI
GPT-5.6 Sol
01
Complex research, coding, computer use and multi-agent professional work
Position
Frontier closed
Weights
Closed
Size
Parameters undisclosed
Context
Provider-managed
Run: ChatGPT, Codex or OpenAI API
Strong all-round agent platform; no local deployment or public weights.
Alignment no longer lowers the headline capability index. It is tracked independently because a system can become more generally capable while remaining difficult to interpret, steer or contain.
Control readiness
48
of 100 · excluded from AGI score
Lagging capability
How much evidence exists that frontier systems remain interpretable, steerable and containable under adversarial pressure. This diagnostic is intentionally excluded from the capability score.
Anthropic
Claude's Constitution
Behavioral constitution
A public statement of Claude's intended character, values and decision principles, written to shape model behavior rather than only list prohibitions.
Open Problems in Constitutional Preference Reconstruction
Constitutions cannot be evaluated separately from the model executing them; cross-model preference agreement remains materially lower than within-model agreement.
The index measures the best demonstrated frontier AI system: a leading model operating with the tools, memory and agent scaffolding normally required for real work. 100 represents reliable performance across most economically valuable cognitive tasks, transfer to unfamiliar domains and sustained execution with limited human intervention.
01
Collect
Primary releases, system cards, incident reports and independent evaluation.
02
Classify
Separate model capability from the agent system, the harness and marketing claims.
03
Score
Weight six demonstrated capabilities, publish the uncertainty band and report control separately.
Scivity Labs (2026). AI Progress & Market Landscape. https://scivity.org/landscape#ai-progress
CC BY 4.0 · Editorial review after material frontier events
AI for Science deep dive
One vertical, fully evidenced.
The whole-market map above provides breadth. This section goes deeper on AI for Science: reasoning engines, experimental execution, verification, proprietary data loops, and institutional infrastructure.
Science-specific scores, finance records, trials, research outputs, benchmarks, and event ledgers apply only to this cohort. They are not used to rank general-market companies with irrelevant scientific criteria.
Entities
67
Company funding
32
Ecosystem events
12
Milestones
165
Sources
333
Capital signals
US$ millions by year
AI-for-Science only. Includes closed company rounds plus ecosystem capital with explicit committed amounts. Biobucks deal value, program ceilings, broader-market capital, talks, and valuation-only events stay out of totals.
Autonomy stack coverage
63 science domains
A single entity can occupy multiple roles. Full-stack labs count across reason, execute, verify, and data where the public record supports it.
Geography and stage
Distribution
Region
North America48
Europe14
Asia-Pacific3
North America / Europe1
North America / Middle East1
Stage
Growth10
Private scaleup8
Seed8
Commercial8
Research facility8
Public5
Series A4
Research platform2
Dimensional scorecard
Average, 0-4
Autonomy
2.6
Execution
2.6
Verification
2.6
Scientific evidence
2.9
Capital
2.7
Traction
2.9
Scores are dimensions, not a ranking. They make tradeoffs legible before a future Scivity index exists.
Autonomy stack
Where each player actually sits.
The useful comparison is not “AI company versus lab automation company.” It is which part of the scientific method each system can own, and which parts still depend on people or external infrastructure.
Reason
48
Agents and models that generate hypotheses, plans, code, protocols, papers, or scientific arguments.
Filter by stack role, domain, organization type, evidence level, capital band, and access model. Select up to four entities for a side-by-side comparison.
Sort
67 shown
Select up to four entities to compare dimensional scores, stack roles, evidence level, and access model.
01
Public company
Ginkgo Bioworks
Public · North America · Boston, MA · Founded 2008 · Updated 2026-05
Public deployment12NYSE: DNACIK 0001830214Public companyHybrid
Synthetic biology foundry. Engineered organisms as a service; increasingly AI-augmented across the design-build-test-learn cycle.
Public · North America · Vancouver, Canada · Founded 2012 · Updated 2026-05
Public deployment5Nasdaq: ABCLCIK 0001703057Public companyPartnership platform
Public antibody-discovery platform company. Integrates single-cell screening, computation, antibody engineering, translational science, and clinical manufacturing from target to clinic.
Private scaleup · North America · San Francisco, CA · Founded 2025 · Updated 2026-05
Working prototype2Announced platformProprietary
Autonomous physical labs for materials and chemistry. AI scientists generate hypotheses; robotic labs run synthesis and characterization; results feed back as training data unavailable anywhere else.
Capital
$300M
Secondary / new round · Mar 2026
Runway
Not public
No public cash ledger
Research
1 output
Announced platform
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
0 deals
No tracked partnerships
Sources
10
linked evidence records
Autonomy
4
Execution
4
Verification
3
Scientific evidence
3
Capital
4
Traction
2
ReasonExecuteDataVerifyMaterialsChemistry
04
Company
Lila Sciences
Private scaleup · North America · Cambridge, MA · Founded 2023 · Updated 2026-05
Working prototype1Announced platformProprietary
AI Science Factories — integrated reasoning models, robotic labs, and verifiers running the scientific method across life, chemistry, and materials sciences.
Capital
$550M
Series A · Sep 2025
Runway
Not public
No public cash ledger
Research
1 output
Announced platform
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
0 deals
No tracked partnerships
Sources
9
linked evidence records
Autonomy
4
Execution
4
Verification
3
Scientific evidence
3
Capital
4
Traction
2
ReasonExecuteVerifyDataBiologyChemistryMaterials
05
Company
Chemify
Growth · Europe · Glasgow, UK · Founded 2023 · Updated 2026-04
Published results5Published platformProprietary
Chemputer platform — universal chemical synthesis via programmable hardware and AI-driven reaction planning. Commercialization of Lee Cronin's Glasgow work.
Research facility · North America · Lemont, IL · Founded 1946 · Updated 2026-05
Published results3Research facilityPublic infrastructure
DOE national lab with an explicit Autonomous Discovery initiative. Uses AI, robotics, simulations, data platforms, and self-driving chemistry tools to automate experiments and scientific decision loops.
Research facility · North America · Oak Ridge, TN · Founded 1943 · Updated 2026-05
Published results2Research facilityPublic infrastructure
DOE national lab building autonomous science platforms across instrumentation, computing, and laboratory automation. INTERSECT and the Autonomous Chemistry Lab connect AI, robotics, and HPC.
Research facility · North America · Gaithersburg, MD · Founded 1901 · Updated 2026-05
Published results4Research facilityPublic infrastructure
US standards and measurement institute with autonomous-laboratory programs in materials, formulations, metrology, and biofoundry automation. Focuses on closed-loop experimentation and interoperability.
Research facility · North America · Berkeley, CA · Founded 2022 · Updated 2026-02
Published results3Published platformPublic infrastructure
Autonomous materials synthesis lab at Lawrence Berkeley National Lab. AI-driven synthesis of novel inorganic materials.
Capital
Government
Undisclosed / other
Runway
Not public
No public cash ledger
Research
1 output
1 correction event
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
0 deals
No tracked partnerships
Sources
11
linked evidence records
Autonomy
4
Execution
4
Verification
2
Scientific evidence
4
Capital
2
Traction
3
ReasonExecuteVerifyDataMaterialsChemistry
11
Frontier AI lab
Google DeepMind
Big Tech lab · Europe · London, UK · Founded 2010 · Updated 2026-05
Published results22Frontier researchHybrid
AlphaFold, AlphaProteo, GNoME, AlphaGeometry, AlphaEvolve, and the Gemini model family — state-of-the-art scientific AI, without a dedicated autonomous-lab product line. Gemini 3.5 Flash was released in May 2026, followed by the limited-access Gemini 3.5 Flash Cyber model in July.
Public · Asia-Pacific · Hong Kong (also Boston, New York) · Founded 2014 · Updated 2026-07
Working prototype12HKEX: 03696.HKClinical dataProprietary
End-to-end generative AI platform for drug discovery and development (Pharma.AI). Public on the Hong Kong Stock Exchange since December 2025. Its AI-discovered and AI-designed TNIK inhibitor rentosertib entered a 320-participant Phase 3 IPF trial in July 2026.
Capital
Public (HKG: 03696.HK)
Public
Runway
Pending
The July 2026 positive profit alert reports ranges rather than full interim financial statements; HKEX financial statements are not yet normalized into public-financials.json.
Research
1 output
Clinical data
Clinical
2 trials
Phase 3
Non-dilutive
0 awards
No tracked grants
Deals
3 deals
Takeda
Sources
20
linked evidence records
Autonomy
2
Execution
2
Verification
3
Scientific evidence
4
Capital
4
Traction
4
ReasonVerifyDataBiologyDrug discoveryClinical development
13
Government lab
NREL
Research facility · North America · Golden, CO · Founded 1977 · Updated 2024-10
Published results2Research facilityPublic infrastructure
DOE national lab with autonomous experimentation capabilities for energy materials. Work includes autonomous synthesis, autonomous characterization, and AI-assisted control software for instruments.
Research facility · North America · Upton, NY · Founded 1947 · Updated 2023-01
Published results4Research facilityPublic infrastructure
DOE national lab and user-facility operator applying AI, robotics, and autonomous experiment steering to materials and photon-science workflows at NSLS-II and CFN.
Growth · North America · San Francisco, CA · Founded 2024 · Updated 2026-01
Working prototype6Wet-lab validated modelCommercial partnership
AI drug and biologics design company building a computer-aided design suite for molecules, with Chai-2 focused on zero-shot antibody and protein-binder design.
Growth · North America · Berkeley, CA · Founded 2022 · Updated 2026-05
Working prototype4Wet-lab validated modelHybrid
Programmable-biology company using frontier protein language models. November 2025 closed a $106M Series B co-led by Altimeter Capital and Bezos Expeditions, taking total funding to $150M. May 2026 announced a strategic collaboration with Eli Lilly for custom site-specific recombinases addressing severe-unmet-need diseases, with up to $2.25B in development and commercial milestones plus tiered royalties. Released OpenCRISPR-1, the first AI-generated CRISPR gene editor.
Capital
$106M
Series B · Nov 2025
Runway
Not public
No public cash ledger
Research
0 outputs
Wet-lab validated model
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
1 deal
Eli Lilly
Sources
12
linked evidence records
Autonomy
2
Execution
2
Verification
3
Scientific evidence
4
Capital
4
Traction
4
ReasonDataVerifyBiologyProtein designGene editing
17
Company
Emerald Cloud Lab
Commercial · North America · South San Francisco, CA · Founded 2010 · Updated 2025-10
Public deployment2CommercialProprietary
Remote-controlled cloud lab — programmable chemistry and biology infrastructure accessed via a full scientific-computing environment.
Frontier platform · North America · San Francisco, CA · Founded 2015 · Updated 2026-05
Working prototype22Frontier platformProprietary
Frontier model developer. The GPT-5.6 Sol, Terra, and Luna family launched in July 2026 across ChatGPT, Codex, and the API, with dedicated science and health evaluations alongside broader agentic capabilities.
Private scaleup · Europe · London, UK · Founded 2021 · Updated 2026-04
Working prototype4Clinical pipelineProprietary
Alphabet-backed AI drug discovery company spun out of Google DeepMind. Builds on AlphaFold to design novel therapeutics, with a 17-program pipeline advancing toward the clinic.
Capital
$600M
First external round · Apr 2025
Runway
Not public
No public cash ledger
Research
1 output
Clinical pipeline
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
2 deals
Eli Lilly
Sources
12
linked evidence records
Autonomy
2
Execution
2
Verification
3
Scientific evidence
4
Capital
4
Traction
3
ReasonVerifyDataBiologyDrug discovery
21
Company
Generate Biomedicines
Clinical-stage platform · North America · Somerville, MA · Founded 2018 · Updated 2026-01
Working prototype8Clinical pipelineProprietary
Generative biology company creating programmable protein therapeutics. Combines machine-learning design with biological engineering and high-throughput wet-lab validation to build a clinical pipeline.
Private scaleup · North America · South San Francisco, CA · Founded 2018 · Updated 2025-12
Public deployment6Commercial partnershipsProprietary
Machine-learning drug discovery company founded by Daphne Koller. Builds large biological datasets from in vitro disease models, human genetics, and partnerships to find targets and patient subgroups.
Research facility · North America · Livermore, CA · Founded 1952 · Updated 2025-07
Published results2Research facilityPublic infrastructure
DOE/NNSA national lab applying AI, robotics, and high-performance computing to scientific discovery. APEX is a self-driving alloy-discovery platform for autonomous design, fabrication, and characterization.
Capital
Government
Undisclosed / other
Runway
Not public
No public cash ledger
Research
1 output
Research facility
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
0 deals
No tracked partnerships
Sources
10
linked evidence records
Autonomy
3
Execution
4
Verification
3
Scientific evidence
4
Capital
2
Traction
2
ReasonExecuteInfrastructureDataVerifyMaterialsAdvanced manufacturingAI for science
25
Frontier AI lab
Anthropic
Frontier platform · North America · San Francisco, CA · Founded 2021 · Updated 2026-04
Working prototype14Frontier platformProprietary
Frontier model developer (Claude family). Claude for Life Sciences connects scientific tools and data sources; Claude Science adds a reproducible multi-agent workbench for researchers; and Sonnet 5, Fable 5, and restricted-access Mythos 5 extend agentic and life-sciences capabilities. Anthropic also acquired Coefficient Bio in April 2026.
Research platform · North America · Seattle, WA · Founded 2014 · Updated 2026-04
Published results6Open researchOpen
Allen Institute for AI — nonprofit research institute founded by Paul Allen. In August 2025 launched Asta, an open agentic ecosystem for science covering scholarly research assistants, the AstaBench benchmark suite (2,400+ problems across 11 benchmarks), and a developer toolkit with open-source agents, post-trained science LMs, and a 200M-paper Scientific Corpus Tool. AstaBench accepted as ICLR 2026 oral.
Private scaleup · Asia-Pacific · Tokyo, Japan · Founded 2023 · Updated 2026-04
Published results6Peer-reviewed demoHybrid
The AI Scientist — autonomous ML research agent. Produces end-to-end research papers with minimal human involvement.
Capital
$135M
Series B · Nov 2025
Runway
Not public
No public cash ledger
Research
4 outputs
Peer-reviewed demo
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
0 deals
No tracked partnerships
Sources
14
linked evidence records
Autonomy
4
Execution
1
Verification
2
Scientific evidence
3
Capital
4
Traction
3
ReasonVerifyML researchGeneral science
28
Nonprofit lab
FutureHouse
Research platform · North America · San Francisco, CA · Founded 2023 · Updated 2026-04
Published results6Open researchHybrid
Nonprofit AI research lab building autonomous scientists for biology. Released the Crow, Falcon, Owl, and Phoenix agent family, added ether0 and DISCO in 2026, and spun out Edison Scientific in late 2025.
Research facility · North America · Richland, WA · Founded 1965 · Updated 2026-05
Published results3Research facilityPublic infrastructure
Pacific Northwest National Laboratory. DOE lab with autonomous experimentation programs in chemistry and energy. Part of the DOE × DeepMind Genesis Mission network.
AI-for-science startup running a 24/7 autonomous chemistry synthesis line. Serves as the chemistry discovery engine for pharma; global HQ and flagship self-driving lab in Singapore.
Published research · North America · Pittsburgh, PA · Founded 2023 · Updated 2023-12
Published results2Nature paperResearch prototype
Academic autonomous chemistry system from Carnegie Mellon. Uses GPT-4 with tool use, code execution, documentation search, and cloud-lab automation to design, plan, and execute chemistry experiments.
Public · Europe · Maennedorf, Switzerland · Founded 1980 · Updated 2026-05
Public deployment4SIX Swiss Exchange: TECNISIN CH0012100191CommercialCommercial hardware
Swiss public lab-automation and life-science instrumentation company. Fluent and related workstations provide liquid handling, robotics, readers, and process automation across pharma and diagnostics.
Capital
Public (SIX: TECN)
Public
Runway
Pending
Non-SEC public company; the Q1 2026 update is qualitative and H1 2026 results are scheduled for August 11, after this dataset's August 4 cutoff. SIX/annual-report fields are not yet normalized into public-financials.json.
Private scaleup · North America · Burlingame, CA · Founded 2019 · Updated 2026-05
Working prototype4Platform pipelineProprietary
AI-first small-molecule drug discovery company formerly known as Genesis Therapeutics. GEMS combines generative AI, molecular simulation, and predictive models to design molecules for difficult targets.
Capital
$200M
Series B · Aug 2023
Runway
Not public
No public cash ledger
Research
1 output
Platform pipeline
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
0 deals
No tracked partnerships
Sources
12
linked evidence records
Autonomy
3
Execution
2
Verification
3
Scientific evidence
3
Capital
3
Traction
3
ReasonExecuteDataVerifyDrug discoveryChemistryMolecular AI
35
Company
Automata
Growth · Europe · London, UK · Founded 2015 · Updated 2026-05
Public deployment3CommercialProprietary
Lab-automation operating system for AI-ready wet labs. Modular robotics, orchestration software, and unified data infrastructure to turn physical labs into programmable, repeatable systems.
Private scaleup · North America · South San Francisco, CA · Founded 2024 · Updated 2026-05
Published results2Published data assetProprietary
AI-driven drug discovery and design company. Uses ML from hypothesis through clinical development.
Capital
$1B
Series A · Apr 2024
Runway
Not public
No public cash ledger
Research
1 output
Published data asset
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
0 deals
No tracked partnerships
Sources
10
linked evidence records
Autonomy
2
Execution
2
Verification
3
Scientific evidence
3
Capital
4
Traction
2
ReasonDataVerifyBiologyDrug discoveryVirtual cell
37
Company
Edison Scientific
Seed · North America · San Francisco, CA · Founded 2025 · Updated 2026-05
Published results6Launch paperProprietary
Commercial spinout of FutureHouse. Kosmos is a multi-agent AI co-scientist that runs extended cycles of literature review, data analysis, and hypothesis generation — executing large code workloads and reading extensive scientific corpora per run. Its 2026 surface also includes PaperQA3-backed Edison Literature and LABBench2.
Growth · North America · Redwood City, CA · Founded 2013 · Updated 2023-01
Public deployment3CommercialProprietary
Materials AI platform for chemicals, formulations, and manufactured products. Provides domain-specific data infrastructure and AI models that help R&D teams predict, optimize, and reuse materials knowledge.
Capital
$16M
Series C · Jan 2023
Runway
Not public
No public cash ledger
Research
1 output
Commercial
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
0 deals
No tracked partnerships
Sources
11
linked evidence records
Autonomy
2
Execution
1
Verification
3
Scientific evidence
3
Capital
3
Traction
4
ReasonDataVerifyMaterialsChemistryManufacturing
39
Company
HighRes Biosolutions
Commercial · North America · Beverly, MA · Founded 2004 · Updated 2026-05
Public deployment4CommercialCommercial hardware and software
Life-science lab automation company combining modular hardware, liquid handling, dynamic scheduling, and Cellario orchestration software for drug discovery, genomics, and synthetic biology workflows.
Commercial platform · Europe · Paris, France · Founded 2016 · Updated 2025-09
Public deployment5Commercial platformHybrid
Generative AI and robotics platform for small-molecule drug discovery. Makya designs molecules, Spaya plans synthesis routes, and robotics execute synthesis, purification, analysis, and biological testing.
Peer-reviewed prototype · Europe · Netherlands · Founded 2026 · Updated 2026-04
Published results1Peer-reviewed prototypeOpen research
Academic low-cost modular self-driving laboratory for automated chemical reaction optimization, with Python control software and Bayesian optimization.
Generally available · North America · Redmond, WA · Founded 2025 · Updated 2026-04
Public deployment5Commercial deploymentGenerally available enterprise platform; desktop app in preview
Microsoft's enterprise agentic R&D platform for hypothesis generation, simulation, analysis, and iterative experimentation across life sciences, materials, semiconductors, and engineering workflows.
Commercial · North America / Europe · United States / United Kingdom · Founded 2025 rebrand · Updated 2026-02
Public deployment2CommercialProprietary
Lab orchestration and informatics platform formed from Labguru and Titian Software. Provides ELN/LIMS, sample management, workflow automation, protocol conversion, and AI agents for regulated labs.
Series A · North America · New York, NY · Founded 2023 · Updated 2026-05
Working prototype4Working prototypeProprietary
Physics- and AI-driven small-molecule drug design company formerly known as Atommap. Microcosmos simulates protein motion and interactions at atomic resolution to guide lab-in-the-loop discovery.
Growth · Europe · London, UK · Founded 2011 · Updated 2026-05
Public deployment3CommercialProprietary
Cloud experiment-design platform for biological R&D. Turns multivariate experiment designs into automation instructions and structured data that can be analyzed and reused.
Growth · North America · Boston, MA · Founded 2014 · Updated 2026-05
Public deployment5CommercialProprietary
Scientific Data and AI Cloud for life sciences R&D. Replatforms raw instrument and experiment data into engineered, compliant datasets for analytics, automation, and scientific AI.
Growth · Europe · London, UK; San Francisco, CA · Founded 2018 · Updated 2026-05
Public deployment5Commercial platformProprietary
Agentic AI platform for life-sciences R&D. Combines biomedical knowledge graphs, scientific retrieval, and governed agents for target identification, biomarker research, evidence review, and portfolio decisions.
Policy and research network · North America · United States · Founded 2011 · Updated 2026-05
Working prototype2Government initiativePublic infrastructure
US federal multi-agency initiative for accelerated materials discovery and deployment. Coordinates infrastructure, data, autonomous experimentation, and policy for materials innovation.
Growth · North America · Boston, MA · Founded 2017 · Updated 2026-04
Public deployment2Commercial infrastructureCommercial partnership
Tech-enabled biotech infrastructure and integrated services platform for biologics discovery and development, combining AI, real-world data, and wet-lab execution.
Commercial early access · North America · Seattle, WA · Founded 2026 · Updated 2026-04
Public deployment7Commercial productCommercial early-access plans, free trial, and free non-commercial academic tier
AWS's agentic application for lab-in-the-loop drug discovery, launched April 14, 2026 and available with a free trial and paid early-access plans. It exposes 40+ biology AI models, supports custom models, and connects computational workflows to CRO and wet-lab partners.
Seed · North America · San Francisco, CA · Founded 2023 · Updated 2026-05
Published results3Peer-reviewed demoProprietary
Autonomous agents for ML research. Carl ideates and writes papers; Mira embeds new research directly into production ML models.
Capital
$14M
Seed · Mar 2026
Runway
Not public
No public cash ledger
Research
2 outputs
Peer-reviewed demo
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
0 deals
No tracked partnerships
Sources
11
linked evidence records
Autonomy
4
Execution
1
Verification
2
Scientific evidence
3
Capital
2
Traction
2
ReasonVerifyML research
55
Company
Radical AI
Seed · North America · New York, NY · Founded 2022 · Updated 2026-05
Published results2Open researchHybrid
AI platform for materials discovery. Focus on industrial biomanufacturing and novel functional materials.
Capital
$13.5M
<$100M
Runway
Not public
No public cash ledger
Research
1 output
Open research
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
0 deals
No tracked partnerships
Sources
10
linked evidence records
Autonomy
3
Execution
3
Verification
2
Scientific evidence
2
Capital
2
Traction
2
ReasonExecuteDataMaterialsSimulation
56
Company
Helical
Seed · Europe · London, UK · Founded 2024 · Updated 2026-05
Public deployment4Production deploymentProprietary
Virtual AI lab for pharma R&D. Converts biological foundation models into reproducible in-silico discovery workflows for target identification, biomarker discovery, and therapeutic design.
Capital
$10M
Seed · Apr 2026
Runway
Not public
No public cash ledger
Research
1 output
Production deployment
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
0 deals
No tracked partnerships
Sources
12
linked evidence records
Autonomy
3
Execution
1
Verification
3
Scientific evidence
2
Capital
2
Traction
3
ReasonDataVerifyBiologyDrug discoveryBiomarkers
57
Company
Kebotix
Commercial · North America · Cambridge, MA · Founded 2017 · Updated 2026-05
Public deployment2Commercial platformProprietary
Self-driving laboratory company for chemicals and materials discovery. Combines AI planning, robotics, and high-throughput experimentation to shorten materials and molecule optimization loops.
Series A · North America · Palo Alto, CA · Founded 2019 · Updated 2026-05
Public deployment2Commercial platformProprietary
Lab orchestration software for life sciences R&D. Connects wet-lab instruments, informatics systems, scheduling, digital twins, and AI agents into controlled scientific workflows.
Commercial · North America · Oakland, CA · Founded 2014 · Updated 2026-05
Public deployment2CommercialProprietary
Scientific process design and data platform now offered as Riffyn X inside Siemens. Captures experimental methods, sample lineage, and process data in forms ready for analysis and machine learning.
Seed · North America · San Francisco, CA · Founded 2025 · Updated 2026-05
Working prototype5Announced platformProprietary
AI-native platform for next-generation protein characterization. Automates mass-spectrometry interpretation so biologic drug candidates can be characterized and quality-assessed faster.
Seed · North America · San Francisco, CA · Founded 2025 · Updated 2026-05
Published results2Benchmark resultProprietary
Applied research lab automating parts of the ML research workflow — experiment planning, training, evaluation, iteration.
Capital
~$3M
<$100M
Runway
Not public
No public cash ledger
Research
1 output
Benchmark result
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
0 deals
No tracked partnerships
Sources
10
linked evidence records
Autonomy
3
Execution
1
Verification
2
Scientific evidence
2
Capital
1
Traction
1
ReasonVerifyML research
64
Frontier AI lab
AMI Labs
Seed · Europe · Paris, France · Founded 2025 · Updated 2026-05
Working prototype2Announced labProprietary
Advanced Machine Intelligence — Yann LeCun's new lab. Building world models based on Joint Embedding Predictive Architecture (JEPA) rather than next-token LLMs; aims to learn from physical reality as the path to human-level intelligence.
Pre-seed · Europe · Yerevan, Armenia · Founded 2025 · Updated 2026-03
Working prototype2Self-reported platformProprietary
Autonomous science platform focused on computational research workflows that design, execute, and verify scientific work end-to-end, with public emphasis on validation outcomes and evidence surfaces.
Capital
Pre-seed, undisclosed
Undisclosed / other
Runway
Not public
No public cash ledger
Research
0 outputs
Self-reported platform
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
0 deals
No tracked partnerships
Sources
10
linked evidence records
Autonomy
3
Execution
2
Verification
2
Conservative score: public materials describe validation outcomes while thresholds, calibration, and check-composition logic remain private.
Pre-seed · North America · San Francisco, CA · Founded 2023 · Updated 2024-11
Working prototype4PilotProprietary
Execution-layer startup building ResearchOS and a future cloud lab so researchers or AI agents can translate natural-language procedures into machine-ready wet-lab workflows.
Seed · North America · San Francisco, CA · Founded 2025 · Updated 2026-05
Working prototype2PilotProprietary
Natural-language-to-robot-arm layer for lab automation. Scientists type protocols in English; software programs off-the-shelf robotics to execute them.
Capital
$0.5M
<$100M
Runway
Not public
No public cash ledger
Research
1 output
Pilot
Clinical
0 trials
No registry link
Non-dilutive
0 awards
No tracked grants
Deals
0 deals
No tracked partnerships
Sources
9
linked evidence records
Autonomy
2
Execution
3
Verification
1
Scientific evidence
1
Capital
1
Traction
1
ExecuteInfrastructureLab automationBiology
Timeline
Capital, claims, and corrections.
The timeline combines company milestones, field-wide events, and ecosystem capital signals. Cross-market events stay separate from company funding so charts and foreign keys remain clean.
Apr 2026Featured
DOE ARPA-E CATALCHEM-E awards $34M to 12 AI + self-driving lab projects
First large federal bet explicitly tying autonomous labs to industrial catalyst development. Targets compressing catalyst discovery from ~10 years to ~1 year across universities and national labs.
OpenAI launches GPT-Rosalind for life sciences research
OpenAI introduced GPT-Rosalind on April 16, a frontier reasoning model tuned for biology, drug discovery, and translational medicine, alongside a Codex life-sciences plugin connecting to 50+ scientific tools. Available as a research preview through OpenAI's trusted access program with Amgen, Moderna, Thermo Fisher, and the Allen Institute as launch partners.
GPT-5 drives 36,000 CFPS experiments in Ginkgo Cloud Lab
OpenAI and Ginkgo reported a closed-loop autonomous CFPS optimization study on February 5: GPT-5 designed experiments, Ginkgo's Cloud Lab executed them with minimal human intervention, results returned to GPT-5, and the next round was proposed by the model. The campaign covered 36,000+ unique reaction compositions across 580 automated plates, six closed-loop rounds, about 40% lower sfGFP production cost, and a 27% titer increase.
Atinary announced its Boston AI-powered lab with two autonomous Scientific Discovery Factories running closed-loop Design-Make-Test-Analyze-Learn cycles. The lab integrates Atinary's no-code AI platform with robotics and instruments from ABB, Agilent, Bruker, Chemspeed, and Mettler-Toledo for small-molecule synthesis and catalysis.
Recursion Q1 2026: REC-4881 establishes clinical proof of concept in FAP
Recursion's Q1 2026 results, reported May 6, established clinical proof of concept for REC-4881 in familial adenomatous polyposis with significant precancerous polyp reduction; Recursion has initiated FDA engagement for a potential registrational study. The company also booked a fifth Sanofi milestone payment on a partnered first-in-class oncology program and reaffirmed runway into early 2028.
Ginkgo positions Nebula as its autonomous-lab core
Ginkgo's Q1 2026 results, reported May 7, highlighted Cloud Lab adoption from ProQR and Amazon's Bio Discovery platform. Jason Kelly positioned Nebula as the world's largest autonomous lab and targeted doubling the Nebula footprint in 2026. Q1 revenue was $19M with $373M in cash, cash equivalents and marketable securities.
Edison Scientific publishes LABBench2 biology research benchmark
Edison Scientific released LABBench2 on May 2, a 1,892-task benchmark spanning literature, databases, sequences, protocols, patents, trials, and source quality across 11 task families. Moves agent evaluation from short-form biology recall toward practical research workflows including retrieval, file handling, and tool use.
Eli Lilly / Profluent strike $2.25B AI recombinase pact
Eli Lilly and Profluent announced a multi-program strategic research collaboration to design and commercialize custom site-specific recombinases for severe-unmet-need diseases. Deal carries an upfront payment, committed R&D funding, up to $2.25B in development and commercial milestones, and tiered royalties on net sales.
12 projects pairing AI with self-driving labs to compress catalyst-development timelines from ~10 years to ~1 year. Recipients include NC State ($2.99M), UW-Madison ($2.84M), Ames National Lab ($2.52M).
All-stock. First Anthropic M&A into a new domain. ~10 employees, ~$40M+ per employee. Stanton + Frey (ex-Prescient Design). Dimension VC reportedly 38,513% IRR.
ProQR gained access to Ginkgo's Nebula autonomous lab for high-throughput data generation supporting Axiomer RNA-editing discovery. Ginkgo also made a strategic equity investment in ProQR.
ARIA Activation Partners: Government program · 100M GBP (~$125M) open call
ARIA opened a 100M GBP call for 8-10 Activation Partners, explicitly adding AI-for-science tools, AI Scientist systems, and autonomous labs as capabilities to bring into ARIA-funded R&D. Open call ceiling, not yet committed awards — excluded from capital totals.
Project Prometheus: physical-AI capital signal · $10B (adjacent, physical-AI)
Bloomberg-cited reporting said Project Prometheus closed a roughly $10B round at about a $38B valuation for a physical-AI lab focused on engineering and manufacturing physical products. Tracked as an adjacent ecosystem signal for context, not autonomous-science capital — excluded from capital totals.
DOE ARPA-E CATALCHEM-E awards $34M to 12 AI + self-driving lab projects
First large federal bet explicitly tying autonomous labs to industrial catalyst development. Targets compressing catalyst discovery from ~10 years to ~1 year across universities and national labs.
First commercial product from Sakana. Autonomous enterprise research agent (Adaptive Branching MCTS + AI Scientist workflow) producing slide decks and long-form reports in a single extended run — the AI Scientist architecture repurposed for corporate strategy.
Chemify publishes three chemputation validation papers
Cronin/Chemify published three peer-reviewed papers in PNAS and Nature Communications sister journals validating the chemputer for autonomous drug synthesis and kinase inhibitor discovery.
Stanford AI Index 2026: AI agents trail PhD scientists on complex tasks
Stanford HAI's 2026 AI Index Report (released April 13) found that the best frontier AI agents score roughly half as well as human PhDs on complex multi-step scientific workflows, even as models passed the PhD-expert baseline on GPQA. A Nature commentary framed it as the field's first quantitative reality check on autonomous-science agents.
FutureHouse, Caltech, Mila, and collaborators introduced DISCO, a multimodal generative model that co-designs protein sequence and structure. The team reported functional new-to-nature carbene-transfer enzymes, including a B-H insertion design reaching 98% product and 5,170 total turnovers.
Sakana AI introduced Fugu, a multi-agent orchestration system that learns to route work across frontier foundation models and itself. Sakana frames the beta as an API product for coding, mathematics, and scientific-reasoning workloads.
Agent4Science launches as agents-only research social network
University of Chicago's Chenhao Tan launched Agent4Science, a Reddit-style site where AI agents share, debate, and review papers — including AI-generated ones — while humans can only observe. An early experiment in agent-to-agent scientific discourse described in Nature on April 20.
Isomorphic Labs publicly preparing first-in-human AI-designed drug trials
Speaking at WIRED Health on April 16, Isomorphic Labs president Max Jaderberg confirmed the AlphaFold-derived oncology pipeline is gearing up to enter the clinic, the first major operational signal that an AI-native drug-discovery program is reaching first-in-human studies.
OpenAI launches GPT-Rosalind for life sciences research
OpenAI introduced GPT-Rosalind on April 16, a frontier reasoning model tuned for biology, drug discovery, and translational medicine, alongside a Codex life-sciences plugin connecting to 50+ scientific tools. Available as a research preview through OpenAI's trusted access program with Amgen, Moderna, Thermo Fisher, and the Allen Institute as launch partners.
Google DeepMind launches Deep Research and Deep Research Max
Google DeepMind released Deep Research and Deep Research Max in public preview on April 21, autonomous research agents built on Gemini 3.1 Pro that combine open-web search with private data via Model Context Protocol. Deep Research Max runs roughly 160 search queries per task, targeting long-horizon research workflows.
OpenAI released GeneBench on April 23, a benchmark of 103 multi-stage scientific data analysis tasks across 10 genomics and quantitative biology domains. Frontier models score around 25-33%, with OpenAI noting that individual tasks often correspond to multi-day projects for expert computational biologists.
Ginkgo closes Biosecurity divestiture to Tower Biosecurity
On April 3, 2026, Ginkgo completed the divestiture of substantially all Biosecurity-segment operations to Tower Biosecurity, also known as Perimeter Systems, receiving common stock representing about 20% of the purchaser on a fully diluted basis and refocusing the company around autonomous labs.
The Materials Genome Initiative published an autonomous experimentation report summarizing AMII workshop findings and next steps for accelerated materials R&D.
Ai2's spring 2026 AstaBench update reported new frontier-model results on a suite of 2,400+ scientific research problems spanning literature understanding, coding and execution, data analysis, and end-to-end discovery.
Nature Synthesis published RoboChem-Flex, a low-cost modular self-driving laboratory for autonomous reaction optimization with Python software, Bayesian optimization, closed-loop and human-in-the-loop modes, and six validation case studies.
Generare raises €20M Series A for microbial chemistry platform
Generare raised a €20M Series A co-led by Alven and Daphni to scale its platform for reading microbial genomes, expressing silent chemistry, and generating proprietary novel small-molecule data.
Alloy Therapeutics raises $40M Series E at $1B valuation
Alloy raised a $40M Series E at a $1B valuation, reporting 200+ partners, 100+ licensed therapeutic programs, 22 clinical programs, and positioning its AI, real-world-data, and wet-lab capabilities as on-demand biotech infrastructure.
Microsoft expands Discovery preview with enterprise R&D partners
Microsoft expanded preview access for Discovery, adding partner integrations, customer examples, and explicit interoperability with physical labs, robotics, and HPC-backed R&D workflows.
Anthropic releases BioMysteryBench for bioinformatics research
Anthropic introduced BioMysteryBench, a 99-task bioinformatics evaluation with expert baselines and reliability analysis, alongside Claude evaluations on the dataset.
AWS launches Amazon Bio Discovery agentic drug-research platform
AWS announced Amazon Bio Discovery on April 28: agentic AI on Bedrock that selects from 40+ biology foundation models, routes candidates to integrated CRO and cloud-lab partners (Ginkgo Nebula, Twist Bioscience, A-Alpha Bio anticipated) for synthesis and testing, and returns results into a lab-in-the-loop cycle. Early Memorial Sloan Kettering project triaged 300,000 antibody candidates in weeks.
Yann LeCun's new lab. $3.5B pre-money — the largest seed round in European tech history. Signal that frontier-lab veterans are entering the science-AI space outside the Big Tech umbrella.
The market map uses a global anchor set across thirteen layers. Inclusion requires a material role in AI compute, models, infrastructure, agents, applications, robotics, science, or governance and a current primary source.
The deeper scorecard below applies only to organizations that materially affect autonomous scientific discovery. General-market anchors are never assigned science-specific scores; the capability index above uses its own published six-dimension method.
Dimensional scoring
Autonomy
How much of the scientific workflow can run without human step-by-step operation.
Execution
Whether the system can touch the physical world, run labs, trigger assays, or operate production scientific workflows.
Verification
How directly the system can evaluate, reproduce, critique, or measure scientific claims.
Scientific evidence
Strength of public evidence: papers, clinical data, benchmark results, open artifacts, or deployed research outputs.
Capital
Scale of committed capital, strategic partnerships, public-market access, or institutional funding.
Traction
Commercial, institutional, research, or user adoption signals beyond a launch announcement.
Source policy
Every deep-profile entity, funding event, milestone, benchmark definition, and measured result carries source IDs. The validator also checks market-layer coverage, anchor URLs, review dates, AGI weights, score ranges, and unique signal IDs.
v1 is manually curated. Codex automations and recurring refresh flows are intentionally deferred until the data contract is stable.
Funding totals exclude valuation-only discussions and milestone-contingent “up to” amounts. Cross-market events are stored separately from company funding to keep company foreign keys clean.
This page is free to reuse under Creative Commons BY 4.0. Citation: Scivity Labs (2026), “AI Progress & Market Landscape,” scivity.org/landscape.