AI Progress & Market Landscapereviewed 2026-08-08

How is AI advancing—and who is building it?

One signal is never enough. Scivity tracks frontier capability, the market stack that turns models into products, and the scientific systems pushing research toward autonomy—with control reported as a separate, lagging indicator.

Scivity AGI Capability Index

sourced

Capability is crossing into sustained agency.

Confidence band 7381. The largest capability gaps are long-horizon reliability, AI-led R&D and robust action beyond digital environments.

Not a probability · not a countdown

The index

Six capability vectors. One moving frontier.

The score uses a weighted arithmetic mean of demonstrated frontier capabilities. It counts the model together with normal tools and agent scaffolding, while safety and control remain visible as a separate diagnostic instead of suppressing the capability score.

028220% weight

Agency & tool use

Top systems plan, browse, code, use computers and coordinate sub-agents across real workflows; agent scaffolding counts when it is part of normal deployment.

OpenAI — GPT-5.6 (opens in a new tab)

This is a capability-proximity index, not a probability of AGI, a countdown or a claim that any single raw model has reached this level. Safety and control are reported separately so weak alignment does not erase observed capability progress. Each dimension is editorially scored from primary evidence and independent measurements; uncertainty is shown explicitly because no accepted operational definition of AGI exists.

Signal feed

What actually moved.

A curated frontier-news feed where every item answers one question: does this change what AI can do, how long it can do it, where it can run, or whether humans can still supervise it?

2026-07-30

Models

OpenAI cuts GPT-5.6 deployment costs weeks after launch

OpenAI reduced GPT-5.6 Luna pricing by 80% and Terra pricing by 20%, widening access to the same model family used for agentic knowledge work.

Why it matters: Capability diffusion depends on price as well as benchmark scores; cheaper inference moves frontier-class agents into more products and higher-volume workflows.

Cost down / access upPrimary source · HighOpenAI — July 30 update (opens in a new tab)

2026-07-27

Cyber

Microsoft puts a dedicated cyber model inside an agentic defense system

Project Perception combines MAI-Cyber-1-Flash with MDASH to find, prioritize and remediate software vulnerabilities. Public preview began August 3.

Why it matters: Cyber work is moving from chat assistance to continuous machine-speed action in production systems.

Agency + cyberPrimary source · HighMicrosoft (opens in a new tab)

2026-07-21

Cyber

OpenAI models found and exploited a novel path outside their evaluation target

During a Hugging Face evaluation, a combination of GPT-5.6 Sol and a pre-release model discovered and exploited a real attack path without source-code access.

Why it matters: It is simultaneously a capability jump and a control warning: persistent agents can exceed the boundary designers thought they were testing.

Capability up / control downIncident report · HighOpenAI (opens in a new tab)

2026-07-21

Models

Google releases a lightweight model specialized for vulnerability work

Gemini 3.5 Flash Cyber is tuned to find, validate and patch vulnerabilities at lower cost than mainline frontier models.

Why it matters: Specialized capable models make autonomous defensive work cheaper enough to run continuously.

Tool use + deploymentPrimary source · HighGoogle DeepMind (opens in a new tab)

2026-07-16

Models

Kimi K3 brings frontier-class capability to open weights

Moonshot AI released a 2.8T-parameter MoE model with 104B active parameters, native vision and a one-million-token context window; the full weights followed on July 27.

Why it matters: The frontier is no longer confined to closed US APIs, though self-hosting K3 remains a datacenter-scale job.

2026-07-09

Models

GPT-5.6 links frontier capability to parallel agents and internal AI R&D

The Sol, Terra and Luna family adds programmatic tool use and multi-agent execution. OpenAI reports a 16.2-point gain on its internal recursive-self-improvement evaluation bundle.

Why it matters: The strongest evidence for AI improving AI is now operational adoption inside a frontier lab, not a benchmark headline alone.

Agency + self-improvementLab-reported · MediumOpenAI (opens in a new tab)

2026

Autonomy

A production coding-agent mission reportedly ran for 16 days

Factory has described a longest recorded multi-agent software mission of 16 days. This is an agent-system result—not proof that one model reasoned continuously for 16 days, and not a Chinese-model claim.

Why it matters: Runtime endurance is becoming real, but it must be separated from independent model reliability and task difficulty.

Autonomy runtimeReported case study · MediumAI Engineer / Factory talk (opens in a new tab)

2026-06-30

Science

Anthropic turns lower-cost agents into a reproducible science workbench

Claude Sonnet 5 moved stronger planning and tool use into Anthropic's lower-cost model tier, while Claude Science packaged multi-agent analysis, auditable artifacts, specialist tools and lab compute access into a dedicated research environment.

Why it matters: AI progress reaches science through usable systems, not raw model scores alone: cheaper agents plus reproducible artifacts make sustained research workflows accessible to more labs.

2026-06-09

Autonomy

Claude Fable 5 is positioned for days-long asynchronous work

Anthropic says Fable 5 can plan, delegate and check work across multi-day coding and knowledge-work projects when used in an agent harness.

Why it matters: Frontier vendors now treat long-running agents as a product surface, while independent evidence still trails the claims.

Long-horizon agencyLab-reported · MediumAnthropic (opens in a new tab)

2026-05-07

Science

AlphaEvolve expands from algorithm records into science and infrastructure

DeepMind reports deployments across physics, neuroscience, cryptography, energy and neural-network optimization, with automatically evaluated discoveries.

Why it matters: Validated novelty is a stronger AGI signal than fluent answers: the system must produce something that survives an external check.

Scientific discoveryPrimary source · HighGoogle DeepMind (opens in a new tab)

2026-02-05

Cyber

Claude finds hundreds of high-severity vulnerabilities in mature codebases

Anthropic reports more than 500 human-validated high-severity findings, including bugs missed after years of traditional fuzzing.

Why it matters: Novel vulnerability discovery is concrete evidence of expert-level search and reasoning beyond memorized answers.

Discovery + cyberLab-reported with human validation · HighAnthropic (opens in a new tab)

Whole-market map

Follow the full AI value chain.

From chips and cloud capacity to models, agents, applications, robotics and control. The map covers every major market layer, while the directory uses a sourced anchor set instead of pretending to list every startup.

98 organizations13 layers6 regionsas of 2026-08-08

>90%

2025

Frontier models built by industry

Industry produced more than 90% of notable frontier models in 2025.

88%

2025

Organizations using AI

Reported organizational AI adoption reached 88%.

$285.9B

2025

U.S. private AI investment

U.S. private AI investment reached $285.9 billion in 2025.

≈66%

2026 report

Agent success on OSWorld

Agent success on OSWorld rose from 12% to roughly 66%, while failures remain material.

Baseline: Stanford HAI 2026 AI Index (opens in a new tab)

Market layers

One system, thirteen markets.

98 matches · all layers

Coverage: representative anchor set

AI for Science & Health

North America

10x Science

AI-native platform for next-generation protein characterization. Automates mass-spectrometry interpretation so biologic drug candidates can be characterized and quality-assessed faster.

AI-native protein characterization platformMass spectrometry analysis agentsProteoform analysis workflows

AI for Science & Health

North America

AbCellera

Public antibody-discovery platform company. Integrates single-cell screening, computation, antibody engineering, translational science, and clinical manufacturing from target to clinic.

Antibody discovery platformSingle-cell screeningClinical manufacturing facility

AI for Science & Health

North America

Acceleration Consortium

International consortium based at University of Toronto. Coordinates self-driving labs across member institutions; publishes protocols and standards.

Self-driving lab networkProtocolsStandards coordination

Scope: Global organizations, platforms and products across the full AI value chain. Inclusion requires a material role in the value chain and a current primary source; layer membership is multi-select.

The AI-for-Science cohort keeps its deeper evidence, finance and benchmark ledgers below. General-market entities are not assigned science-specific scores.

Model atlas

What can run where.

Not another leaderboard. This is the practical layer: which frontier family is suited to what work, whether the weights exist, how large it is, and whether you can run it locally or only through a provider.

Alignment watch

Capability is ahead of control.

Alignment no longer lowers the headline capability index. It is tracked independently because a system can become more generally capable while remaining difficult to interpret, steer or contain.

Control readiness

48

of 100 · excluded from AGI score

Lagging capability

How much evidence exists that frontier systems remain interpretable, steerable and containable under adversarial pressure. This diagnostic is intentionally excluded from the capability score.

Anthropic

Claude's Constitution

Behavioral constitution

A public statement of Claude's intended character, values and decision principles, written to shape model behavior rather than only list prohibitions.

OpenAI

Model Spec

Behavior specification

A public hierarchy of objectives, rules and defaults for model behavior, released for reuse under CC0.

Google DeepMind

Frontier Safety Framework 3.1

Capability-triggered governance

Tracked and critical capability levels across cyber, CBRN, manipulation, ML R&D and misalignment, linked to stronger evaluations and mitigations.

OpenAI

Frontier Governance Framework

Risk governance

Maps frontier-model safety and security practices to emerging legal and governance requirements.

xAI

Risk Management Framework

Malicious-use and loss-of-control policy

Public thresholds and procedures for abuse potential, concerning propensities, dual-use capability and loss-of-control risk.

Research pulse

Can the rules survive the agent?

2026-07-29

Constitutional Midtraining

A constitutional training corpus improved alignment durability under pressure and reduced induced blackmail behavior after later fine-tuning.

arXiv (opens in a new tab)

2026-06-29

Open Problems in Constitutional Preference Reconstruction

Constitutions cannot be evaluated separately from the model executing them; cross-model preference agreement remains materially lower than within-model agreement.

arXiv (opens in a new tab)

2026-05-28

How Well Do Models Follow Their Constitutions?

Newer model families violate their public behavioral specifications less often, but adherence remains measurable rather than guaranteed.

arXiv (opens in a new tab)

2026-03-19

Monitoring internal coding agents for misalignment

Real deployments show constraint circumvention and over-eagerness, while severe scheming has not been observed in the reported production traffic.

OpenAI (opens in a new tab)

Method & sources

Transparent enough to disagree with.

The index measures the best demonstrated frontier AI system: a leading model operating with the tools, memory and agent scaffolding normally required for real work. 100 represents reliable performance across most economically valuable cognitive tasks, transfer to unfamiliar domains and sustained execution with limited human intervention.

  1. 01

    Collect

    Primary releases, system cards, incident reports and independent evaluation.

  2. 02

    Classify

    Separate model capability from the agent system, the harness and marketing claims.

  3. 03

    Score

    Weight six demonstrated capabilities, publish the uncertainty band and report control separately.

Cite the observatory

Scivity Labs (2026). AI Progress & Market Landscape. https://scivity.org/landscape#ai-progress

CC BY 4.0 · Editorial review after material frontier events

AI for Science deep dive

One vertical,
fully evidenced.

The whole-market map above provides breadth. This section goes deeper on AI for Science: reasoning engines, experimental execution, verification, proprietary data loops, and institutional infrastructure.

Science-specific scores, finance records, trials, research outputs, benchmarks, and event ledgers apply only to this cohort. They are not used to rank general-market companies with irrelevant scientific criteria.

Entities

67

Company funding

32

Ecosystem events

12

Milestones

165

Sources

333

Capital signals

US$ millions by year

AI-for-Science only. Includes closed company rounds plus ecosystem capital with explicit committed amounts. Biobucks deal value, program ceilings, broader-market capital, talks, and valuation-only events stay out of totals.

Autonomy stack coverage

63 science domains

A single entity can occupy multiple roles. Full-stack labs count across reason, execute, verify, and data where the public record supports it.

Geography and stage

Distribution

Region

North America48
Europe14
Asia-Pacific3
North America / Europe1
North America / Middle East1

Stage

Growth10
Private scaleup8
Seed8
Commercial8
Research facility8
Public5
Series A4
Research platform2

Dimensional scorecard

Average, 0-4
Autonomy
2.6
Execution
2.6
Verification
2.6
Scientific evidence
2.9
Capital
2.7
Traction
2.9

Scores are dimensions, not a ranking. They make tradeoffs legible before a future Scivity index exists.

Autonomy stack

Where each player
actually sits.

The useful comparison is not “AI company versus lab automation company.” It is which part of the scientific method each system can own, and which parts still depend on people or external infrastructure.

Entity explorer

Compare the field
without collapsing it.

Filter by stack role, domain, organization type, evidence level, capital band, and access model. Select up to four entities for a side-by-side comparison.

Sort
67 shown
Select up to four entities to compare dimensional scores, stack roles, evidence level, and access model.

01

Public company

Ginkgo Bioworks

Public · North America · Boston, MA · Founded 2008 · Updated 2026-05

Public deployment12NYSE: DNACIK 0001830214Public companyHybrid

Synthetic biology foundry. Engineered organisms as a service; increasingly AI-augmented across the design-build-test-learn cycle.

Cash + securities

$373M

$144M cash / $230M securities

Runway

9.2 mo

$47M burn / qtr

Research

3 outputs

1 measured results

Clinical

0 trials

No registry link

Non-dilutive

1 award

$47M

Deals

3 deals

ProQR Therapeutics

Sources

20

linked evidence records

Autonomy

3

Execution

4

Verification

3

Scientific evidence

4

Capital

3

Traction

4
ReasonExecuteDataInfrastructureBiologySynthetic biologyCloud lab

02

Public company

AbCellera

Public · North America · Vancouver, Canada · Founded 2012 · Updated 2026-05

Public deployment5Nasdaq: ABCLCIK 0001703057Public companyPartnership platform

Public antibody-discovery platform company. Integrates single-cell screening, computation, antibody engineering, translational science, and clinical manufacturing from target to clinic.

Cash + securities

$505M

$77M cash / $428M securities

Runway

6.9 mo

$34M burn / qtr

Research

1 output

Public company

Clinical

1 trial

Phase 1

Non-dilutive

0 awards

No tracked grants

Deals

1 deal

Eli Lilly

Sources

13

linked evidence records

Autonomy

2

Execution

4

Verification

3

Scientific evidence

4

Capital

4

Traction

4
ReasonExecuteDataVerifyBiologyAntibody discoveryClinical manufacturing

03

Company

Periodic Labs

Private scaleup · North America · San Francisco, CA · Founded 2025 · Updated 2026-05

Working prototype2Announced platformProprietary

Autonomous physical labs for materials and chemistry. AI scientists generate hypotheses; robotic labs run synthesis and characterization; results feed back as training data unavailable anywhere else.

Capital

$300M

Secondary / new round · Mar 2026

Runway

Not public

No public cash ledger

Research

1 output

Announced platform

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

4

Execution

4

Verification

3

Scientific evidence

3

Capital

4

Traction

2
ReasonExecuteDataVerifyMaterialsChemistry

04

Company

Lila Sciences

Private scaleup · North America · Cambridge, MA · Founded 2023 · Updated 2026-05

Working prototype1Announced platformProprietary

AI Science Factories — integrated reasoning models, robotic labs, and verifiers running the scientific method across life, chemistry, and materials sciences.

Capital

$550M

Series A · Sep 2025

Runway

Not public

No public cash ledger

Research

1 output

Announced platform

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

9

linked evidence records

Autonomy

4

Execution

4

Verification

3

Scientific evidence

3

Capital

4

Traction

2
ReasonExecuteVerifyDataBiologyChemistryMaterials

05

Company

Chemify

Growth · Europe · Glasgow, UK · Founded 2023 · Updated 2026-04

Published results5Published platformProprietary

Chemputer platform — universal chemical synthesis via programmable hardware and AI-driven reaction planning. Commercialization of Lee Cronin's Glasgow work.

Capital

$50M

Series B · Oct 2025

Runway

Not public

No public cash ledger

Research

3 outputs

Published platform

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

13

linked evidence records

Autonomy

3

Execution

4

Verification

3

Scientific evidence

4

Capital

3

Traction

3
ReasonExecuteVerifyInfrastructureChemistryDrug discoveryProgrammable synthesis

06

Public company

Recursion Pharmaceuticals

Public · North America · Salt Lake City, UT · Founded 2013 · Updated 2026-05

Public deployment8Nasdaq: RXRXCIK 0001601830Public companyProprietary

Publicly traded AI-native drug discovery platform. Industrial-scale phenomics, ML-driven target identification, and image-based screening at PB-scale.

Cash & equivalents

$654M

Q1 2026 10-Q

Runway

24.2 mo

$81M burn / qtr

Research

3 outputs

Public company

Clinical

1 trial

Phase 1b/2

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

16

linked evidence records

Autonomy

2

Execution

3

Verification

3

Scientific evidence

4

Capital

4

Traction

4
ReasonExecuteDataVerifyBiologyDrug discoveryImaging

07

Government lab

Argonne National Laboratory

Research facility · North America · Lemont, IL · Founded 1946 · Updated 2026-05

Published results3Research facilityPublic infrastructure

DOE national lab with an explicit Autonomous Discovery initiative. Uses AI, robotics, simulations, data platforms, and self-driving chemistry tools to automate experiments and scientific decision loops.

Capital

Government

Undisclosed / other

Runway

Not public

No public cash ledger

Research

1 output

Research facility

Clinical

0 trials

No registry link

Non-dilutive

1 award

$3M

Deals

0 deals

No tracked partnerships

Sources

11

linked evidence records

Autonomy

4

Execution

4

Verification

3

Scientific evidence

4

Capital

2

Traction

3
ReasonExecuteInfrastructureDataVerifyMaterialsChemistryBiologyEnergy

08

Government lab

Oak Ridge National Laboratory

Research facility · North America · Oak Ridge, TN · Founded 1943 · Updated 2026-05

Published results2Research facilityPublic infrastructure

DOE national lab building autonomous science platforms across instrumentation, computing, and laboratory automation. INTERSECT and the Autonomous Chemistry Lab connect AI, robotics, and HPC.

Capital

Government

Undisclosed / other

Runway

Not public

No public cash ledger

Research

1 output

Research facility

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

4

Execution

4

Verification

3

Scientific evidence

4

Capital

2

Traction

3
ReasonExecuteInfrastructureDataVerifyMaterialsChemistryEnergyComputing

09

Government lab

NIST

Research facility · North America · Gaithersburg, MD · Founded 1901 · Updated 2026-05

Published results4Research facilityPublic infrastructure

US standards and measurement institute with autonomous-laboratory programs in materials, formulations, metrology, and biofoundry automation. Focuses on closed-loop experimentation and interoperability.

Capital

Government

Undisclosed / other

Runway

Not public

No public cash ledger

Research

2 outputs

Research facility

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

13

linked evidence records

Autonomy

3

Execution

4

Verification

4

Scientific evidence

4

Capital

2

Traction

3
ExecuteVerifyInfrastructureDataMaterialsMetrologyFormulationsBiology

10

Government lab

A-Lab (LBNL)

Research facility · North America · Berkeley, CA · Founded 2022 · Updated 2026-02

Published results3Published platformPublic infrastructure

Autonomous materials synthesis lab at Lawrence Berkeley National Lab. AI-driven synthesis of novel inorganic materials.

Capital

Government

Undisclosed / other

Runway

Not public

No public cash ledger

Research

1 output

1 correction event

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

11

linked evidence records

Autonomy

4

Execution

4

Verification

2

Scientific evidence

4

Capital

2

Traction

3
ReasonExecuteVerifyDataMaterialsChemistry

11

Frontier AI lab

Google DeepMind

Big Tech lab · Europe · London, UK · Founded 2010 · Updated 2026-05

Published results22Frontier researchHybrid

AlphaFold, AlphaProteo, GNoME, AlphaGeometry, AlphaEvolve, and the Gemini model family — state-of-the-art scientific AI, without a dedicated autonomous-lab product line. Gemini 3.5 Flash was released in May 2026, followed by the limited-access Gemini 3.5 Flash Cyber model in July.

Capital

Alphabet subsidiary

Undisclosed / other

Runway

Not public

No public cash ledger

Research

9 outputs

10 measured results

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

28

linked evidence records

Autonomy

3

Execution

1

Verification

3

Scientific evidence

4

Capital

4

Traction

4
ReasonVerifyDataBiologyMaterialsMathematicsGeneral science

12

Public company

Insilico Medicine

Public · Asia-Pacific · Hong Kong (also Boston, New York) · Founded 2014 · Updated 2026-07

Working prototype12HKEX: 03696.HKClinical dataProprietary

End-to-end generative AI platform for drug discovery and development (Pharma.AI). Public on the Hong Kong Stock Exchange since December 2025. Its AI-discovered and AI-designed TNIK inhibitor rentosertib entered a 320-participant Phase 3 IPF trial in July 2026.

Capital

Public (HKG: 03696.HK)

Public

Runway

Pending

The July 2026 positive profit alert reports ranges rather than full interim financial statements; HKEX financial statements are not yet normalized into public-financials.json.

Research

1 output

Clinical data

Clinical

2 trials

Phase 3

Non-dilutive

0 awards

No tracked grants

Deals

3 deals

Takeda

Sources

20

linked evidence records

Autonomy

2

Execution

2

Verification

3

Scientific evidence

4

Capital

4

Traction

4
ReasonVerifyDataBiologyDrug discoveryClinical development

13

Government lab

NREL

Research facility · North America · Golden, CO · Founded 1977 · Updated 2024-10

Published results2Research facilityPublic infrastructure

DOE national lab with autonomous experimentation capabilities for energy materials. Work includes autonomous synthesis, autonomous characterization, and AI-assisted control software for instruments.

Capital

Government

Undisclosed / other

Runway

Not public

No public cash ledger

Research

2 outputs

Research facility

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

3

Execution

4

Verification

3

Scientific evidence

4

Capital

2

Traction

3
ExecuteDataVerifyInfrastructureMaterialsEnergyCharacterization

14

Government lab

Brookhaven National Laboratory

Research facility · North America · Upton, NY · Founded 1947 · Updated 2023-01

Published results4Research facilityPublic infrastructure

DOE national lab and user-facility operator applying AI, robotics, and autonomous experiment steering to materials and photon-science workflows at NSLS-II and CFN.

Capital

Government

Undisclosed / other

Runway

Not public

No public cash ledger

Research

1 output

Research facility

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

12

linked evidence records

Autonomy

3

Execution

4

Verification

3

Scientific evidence

4

Capital

2

Traction

3
ExecuteDataVerifyInfrastructureMaterialsPhoton scienceNanoscience

15

Company

Chai Discovery

Growth · North America · San Francisco, CA · Founded 2024 · Updated 2026-01

Working prototype6Wet-lab validated modelCommercial partnership

AI drug and biologics design company building a computer-aided design suite for molecules, with Chai-2 focused on zero-shot antibody and protein-binder design.

Capital

$130M

Series B · Dec 2025

Runway

Not public

No public cash ledger

Research

1 output

Wet-lab validated model

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

1 deal

Eli Lilly

Sources

14

linked evidence records

Autonomy

3

Execution

1

Verification

3

Scientific evidence

4

Capital

4

Traction

4
ReasonDataVerifyBiologyDrug discoveryProtein design

16

Company

Profluent

Growth · North America · Berkeley, CA · Founded 2022 · Updated 2026-05

Working prototype4Wet-lab validated modelHybrid

Programmable-biology company using frontier protein language models. November 2025 closed a $106M Series B co-led by Altimeter Capital and Bezos Expeditions, taking total funding to $150M. May 2026 announced a strategic collaboration with Eli Lilly for custom site-specific recombinases addressing severe-unmet-need diseases, with up to $2.25B in development and commercial milestones plus tiered royalties. Released OpenCRISPR-1, the first AI-generated CRISPR gene editor.

Capital

$106M

Series B · Nov 2025

Runway

Not public

No public cash ledger

Research

0 outputs

Wet-lab validated model

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

1 deal

Eli Lilly

Sources

12

linked evidence records

Autonomy

2

Execution

2

Verification

3

Scientific evidence

4

Capital

4

Traction

4
ReasonDataVerifyBiologyProtein designGene editing

17

Company

Emerald Cloud Lab

Commercial · North America · South San Francisco, CA · Founded 2010 · Updated 2025-10

Public deployment2CommercialProprietary

Remote-controlled cloud lab — programmable chemistry and biology infrastructure accessed via a full scientific-computing environment.

Capital

Private, undisclosed

Undisclosed / other

Runway

Not public

No public cash ledger

Research

1 output

Commercial

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

11

linked evidence records

Autonomy

2

Execution

4

Verification

3

Scientific evidence

3

Capital

2

Traction

4
ExecuteInfrastructureDataVerifyChemistryBiologyCloud lab

18

Academic network

Acceleration Consortium

Research network · North America · Toronto, Canada · Founded 2021 · Updated 2025-04

Published results3Research networkPublic infrastructure

International consortium based at University of Toronto. Coordinates self-driving labs across member institutions; publishes protocols and standards.

Capital

$200M+ (CFREF grant)

$100M-$499M

Runway

Not public

No public cash ledger

Research

2 outputs

Research network

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

12

linked evidence records

Autonomy

2

Execution

3

Verification

3

Scientific evidence

4

Capital

3

Traction

3
ExecuteVerifyInfrastructureDataMaterialsChemistryStandards

19

Frontier AI lab

OpenAI

Frontier platform · North America · San Francisco, CA · Founded 2015 · Updated 2026-05

Working prototype22Frontier platformProprietary

Frontier model developer. The GPT-5.6 Sol, Terra, and Luna family launched in July 2026 across ChatGPT, Codex, and the API, with dedicated science and health evaluations alongside broader agentic capabilities.

Capital

$40B+ raised

$500M+

Runway

Not public

No public cash ledger

Research

3 outputs

14 measured results

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

26

linked evidence records

Autonomy

3

Execution

1

Verification

3

Scientific evidence

3

Capital

4

Traction

4
ReasonVerifyInfrastructureGeneral scienceBiologyReasoning

20

Company

Isomorphic Labs

Private scaleup · Europe · London, UK · Founded 2021 · Updated 2026-04

Working prototype4Clinical pipelineProprietary

Alphabet-backed AI drug discovery company spun out of Google DeepMind. Builds on AlphaFold to design novel therapeutics, with a 17-program pipeline advancing toward the clinic.

Capital

$600M

First external round · Apr 2025

Runway

Not public

No public cash ledger

Research

1 output

Clinical pipeline

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

2 deals

Eli Lilly

Sources

12

linked evidence records

Autonomy

2

Execution

2

Verification

3

Scientific evidence

4

Capital

4

Traction

3
ReasonVerifyDataBiologyDrug discovery

21

Company

Generate Biomedicines

Clinical-stage platform · North America · Somerville, MA · Founded 2018 · Updated 2026-01

Working prototype8Clinical pipelineProprietary

Generative biology company creating programmable protein therapeutics. Combines machine-learning design with biological engineering and high-throughput wet-lab validation to build a clinical pipeline.

Capital

$643M

Series C · Sep 2023

Runway

Not public

No public cash ledger

Research

1 output

Clinical pipeline

Clinical

1 trial

Phase 3

Non-dilutive

0 awards

No tracked grants

Deals

1 deal

Amgen

Sources

16

linked evidence records

Autonomy

2

Execution

3

Verification

3

Scientific evidence

3

Capital

4

Traction

3
ReasonExecuteDataVerifyBiologyProtein designDrug discovery

22

Company

Insitro

Private scaleup · North America · South San Francisco, CA · Founded 2018 · Updated 2025-12

Public deployment6Commercial partnershipsProprietary

Machine-learning drug discovery company founded by Daphne Koller. Builds large biological datasets from in vitro disease models, human genetics, and partnerships to find targets and patient subgroups.

Capital

$600M+ disclosed

$500M+

Runway

Not public

No public cash ledger

Research

1 output

Commercial partnerships

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

1 deal

Bristol Myers Squibb

Sources

14

linked evidence records

Autonomy

2

Execution

3

Verification

3

Scientific evidence

3

Capital

4

Traction

3
ReasonExecuteDataVerifyBiologyDrug discoveryHuman genetics

23

Company

Iambic Therapeutics

Clinical-stage platform · North America · San Diego, CA · Founded 2019 · Updated 2024-03

Working prototype5Clinical pipelineProprietary

AI-driven small-molecule drug discovery company. Uses multimodal transformers, protein-ligand structure prediction, high-throughput chemistry, and weekly biological data loops to advance candidates.

Capital

$100M

Series B · Oct 2023

Runway

Not public

No public cash ledger

Research

2 outputs

Clinical pipeline

Clinical

1 trial

Phase 1/1b

Non-dilutive

0 awards

No tracked grants

Deals

1 deal

NVIDIA

Sources

13

linked evidence records

Autonomy

3

Execution

3

Verification

3

Scientific evidence

3

Capital

3

Traction

3
ReasonExecuteDataVerifyDrug discoveryChemistryBiology

24

Government lab

Lawrence Livermore National Laboratory

Research facility · North America · Livermore, CA · Founded 1952 · Updated 2025-07

Published results2Research facilityPublic infrastructure

DOE/NNSA national lab applying AI, robotics, and high-performance computing to scientific discovery. APEX is a self-driving alloy-discovery platform for autonomous design, fabrication, and characterization.

Capital

Government

Undisclosed / other

Runway

Not public

No public cash ledger

Research

1 output

Research facility

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

3

Execution

4

Verification

3

Scientific evidence

4

Capital

2

Traction

2
ReasonExecuteInfrastructureDataVerifyMaterialsAdvanced manufacturingAI for science

25

Frontier AI lab

Anthropic

Frontier platform · North America · San Francisco, CA · Founded 2021 · Updated 2026-04

Working prototype14Frontier platformProprietary

Frontier model developer (Claude family). Claude for Life Sciences connects scientific tools and data sources; Claude Science adds a reproducible multi-agent workbench for researchers; and Sonnet 5, Fable 5, and restricted-access Mythos 5 extend agentic and life-sciences capabilities. Anthropic also acquired Coefficient Bio in April 2026.

Capital

$10B+ raised across rounds

$500M+

Runway

Not public

No public cash ledger

Research

0 outputs

3 measured results

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

22

linked evidence records

Autonomy

3

Execution

1

Verification

3

Scientific evidence

3

Capital

4

Traction

4
ReasonVerifyDataBiologyDrug discoveryGeneral scienceReasoning

26

Nonprofit research institute

Ai2

Research platform · North America · Seattle, WA · Founded 2014 · Updated 2026-04

Published results6Open researchOpen

Allen Institute for AI — nonprofit research institute founded by Paul Allen. In August 2025 launched Asta, an open agentic ecosystem for science covering scholarly research assistants, the AstaBench benchmark suite (2,400+ problems across 11 benchmarks), and a developer toolkit with open-source agents, post-trained science LMs, and a 200M-paper Scientific Corpus Tool. AstaBench accepted as ICLR 2026 oral.

Capital

Endowment-backed nonprofit

Undisclosed / other

Runway

Not public

No public cash ledger

Research

0 outputs

Open research

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

14

linked evidence records

Autonomy

3

Execution

1

Verification

4

Scientific evidence

4

Capital

3

Traction

3
ReasonVerifyDataGeneral scienceLiteratureBiologyReasoning

27

Company

Sakana AI

Private scaleup · Asia-Pacific · Tokyo, Japan · Founded 2023 · Updated 2026-04

Published results6Peer-reviewed demoHybrid

The AI Scientist — autonomous ML research agent. Produces end-to-end research papers with minimal human involvement.

Capital

$135M

Series B · Nov 2025

Runway

Not public

No public cash ledger

Research

4 outputs

Peer-reviewed demo

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

14

linked evidence records

Autonomy

4

Execution

1

Verification

2

Scientific evidence

3

Capital

4

Traction

3
ReasonVerifyML researchGeneral science

28

Nonprofit lab

FutureHouse

Research platform · North America · San Francisco, CA · Founded 2023 · Updated 2026-04

Published results6Open researchHybrid

Nonprofit AI research lab building autonomous scientists for biology. Released the Crow, Falcon, Owl, and Phoenix agent family, added ether0 and DISCO in 2026, and spun out Edison Scientific in late 2025.

Capital

~$20M grants + $70M spinout seed

<$100M

Runway

Not public

No public cash ledger

Research

3 outputs

2 measured results

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

14

linked evidence records

Autonomy

4

Execution

1

Verification

3

Scientific evidence

4

Capital

2

Traction

3
ReasonExecuteVerifyDataBiologyLiteratureGeneral science

29

Government lab

PNNL

Research facility · North America · Richland, WA · Founded 1965 · Updated 2026-05

Published results3Research facilityPublic infrastructure

Pacific Northwest National Laboratory. DOE lab with autonomous experimentation programs in chemistry and energy. Part of the DOE × DeepMind Genesis Mission network.

Capital

Government

Undisclosed / other

Runway

Not public

No public cash ledger

Research

2 outputs

Research facility

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

12

linked evidence records

Autonomy

2

Execution

3

Verification

3

Scientific evidence

4

Capital

2

Traction

3
ExecuteVerifyInfrastructureDataChemistryEnergyMaterials

30

Company

ChemLex

Growth · Asia-Pacific · Singapore · Founded 2022 · Updated 2026-05

Public deployment2CommercialProprietary

AI-for-science startup running a 24/7 autonomous chemistry synthesis line. Serves as the chemistry discovery engine for pharma; global HQ and flagship self-driving lab in Singapore.

Capital

$45M

Growth · Dec 2025

Runway

Not public

No public cash ledger

Research

1 output

Commercial

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

3

Execution

4

Verification

2

Scientific evidence

2

Capital

3

Traction

3
ReasonExecuteInfrastructureDataChemistryDrug discoveryProgrammable synthesis

31

Academic project

Coscientist (CMU)

Published research · North America · Pittsburgh, PA · Founded 2023 · Updated 2023-12

Published results2Nature paperResearch prototype

Academic autonomous chemistry system from Carnegie Mellon. Uses GPT-4 with tool use, code execution, documentation search, and cloud-lab automation to design, plan, and execute chemistry experiments.

Capital

Academic research

Undisclosed / other

Runway

Not public

No public cash ledger

Research

1 output

Nature paper

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

4

Execution

3

Verification

3

Scientific evidence

4

Capital

1

Traction

2
ReasonExecuteVerifyDataChemistryAutonomous agentsCloud lab

32

Company

Opentrons

Commercial · North America · New York, NY · Founded 2013 · Updated 2026-05

Public deployment3CommercialHybrid

Open-source liquid-handling robotics company. Flex and OT-2 robots make programmable wet-lab automation accessible through modular hardware, Python APIs, and protocol libraries.

Capital

Private, venture-backed

Undisclosed / other

Runway

Not public

No public cash ledger

Research

1 output

Commercial

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

2

Execution

4

Verification

2

Scientific evidence

3

Capital

2

Traction

4
ExecuteInfrastructureLab automationBiologyLiquid handling

33

Public company

Tecan

Public · Europe · Maennedorf, Switzerland · Founded 1980 · Updated 2026-05

Public deployment4SIX Swiss Exchange: TECNISIN CH0012100191CommercialCommercial hardware

Swiss public lab-automation and life-science instrumentation company. Fluent and related workstations provide liquid handling, robotics, readers, and process automation across pharma and diagnostics.

Capital

Public (SIX: TECN)

Public

Runway

Pending

Non-SEC public company; the Q1 2026 update is qualitative and H1 2026 results are scheduled for August 11, after this dataset's August 4 cutoff. SIX/annual-report fields are not yet normalized into public-financials.json.

Research

1 output

Commercial

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

7

linked evidence records

Autonomy

1

Execution

4

Verification

2

Scientific evidence

3

Capital

3

Traction

4
ExecuteInfrastructureLab automationDiagnosticsLife sciences

34

Company

Genesis Molecular AI

Private scaleup · North America · Burlingame, CA · Founded 2019 · Updated 2026-05

Working prototype4Platform pipelineProprietary

AI-first small-molecule drug discovery company formerly known as Genesis Therapeutics. GEMS combines generative AI, molecular simulation, and predictive models to design molecules for difficult targets.

Capital

$200M

Series B · Aug 2023

Runway

Not public

No public cash ledger

Research

1 output

Platform pipeline

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

12

linked evidence records

Autonomy

3

Execution

2

Verification

3

Scientific evidence

3

Capital

3

Traction

3
ReasonExecuteDataVerifyDrug discoveryChemistryMolecular AI

35

Company

Automata

Growth · Europe · London, UK · Founded 2015 · Updated 2026-05

Public deployment3CommercialProprietary

Lab-automation operating system for AI-ready wet labs. Modular robotics, orchestration software, and unified data infrastructure to turn physical labs into programmable, repeatable systems.

Capital

$45M

Series C · Jan 2026

Runway

Not public

No public cash ledger

Research

1 output

Commercial

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

1 deal

Molecular Devices

Sources

10

linked evidence records

Autonomy

2

Execution

4

Verification

2

Scientific evidence

2

Capital

2

Traction

4
ExecuteInfrastructureDataBiologyDiagnosticsLab automation

36

Company

Xaira Therapeutics

Private scaleup · North America · South San Francisco, CA · Founded 2024 · Updated 2026-05

Published results2Published data assetProprietary

AI-driven drug discovery and design company. Uses ML from hypothesis through clinical development.

Capital

$1B

Series A · Apr 2024

Runway

Not public

No public cash ledger

Research

1 output

Published data asset

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

2

Execution

2

Verification

3

Scientific evidence

3

Capital

4

Traction

2
ReasonDataVerifyBiologyDrug discoveryVirtual cell

37

Company

Edison Scientific

Seed · North America · San Francisco, CA · Founded 2025 · Updated 2026-05

Published results6Launch paperProprietary

Commercial spinout of FutureHouse. Kosmos is a multi-agent AI co-scientist that runs extended cycles of literature review, data analysis, and hypothesis generation — executing large code workloads and reading extensive scientific corpora per run. Its 2026 surface also includes PaperQA3-backed Edison Literature and LABBench2.

Capital

$70M

Seed · Dec 2025

Runway

Not public

No public cash ledger

Research

1 output

Launch paper

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

1 deal

NVIDIA

Sources

14

linked evidence records

Autonomy

4

Execution

1

Verification

3

Scientific evidence

3

Capital

3

Traction

2
ReasonVerifyDataBiologyMaterialsStatistical geneticsGeneral science

38

Company

Citrine Informatics

Growth · North America · Redwood City, CA · Founded 2013 · Updated 2023-01

Public deployment3CommercialProprietary

Materials AI platform for chemicals, formulations, and manufactured products. Provides domain-specific data infrastructure and AI models that help R&D teams predict, optimize, and reuse materials knowledge.

Capital

$16M

Series C · Jan 2023

Runway

Not public

No public cash ledger

Research

1 output

Commercial

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

11

linked evidence records

Autonomy

2

Execution

1

Verification

3

Scientific evidence

3

Capital

3

Traction

4
ReasonDataVerifyMaterialsChemistryManufacturing

39

Company

HighRes Biosolutions

Commercial · North America · Beverly, MA · Founded 2004 · Updated 2026-05

Public deployment4CommercialCommercial hardware and software

Life-science lab automation company combining modular hardware, liquid handling, dynamic scheduling, and Cellario orchestration software for drug discovery, genomics, and synthetic biology workflows.

Capital

Private; Axel Johnson portfolio company

Undisclosed / other

Runway

Not public

No public cash ledger

Research

1 output

Commercial

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

1 deal

TetraScience

Sources

11

linked evidence records

Autonomy

2

Execution

4

Verification

2

Scientific evidence

2

Capital

2

Traction

4
ExecuteInfrastructureDataLab automationDrug discoverySynthetic biologyGenomics

40

Company

Iktos

Commercial platform · Europe · Paris, France · Founded 2016 · Updated 2025-09

Public deployment5Commercial platformHybrid

Generative AI and robotics platform for small-molecule drug discovery. Makya designs molecules, Spaya plans synthesis routes, and robotics execute synthesis, purification, analysis, and biological testing.

Capital

EUR15.5M Series A plus EIC support

Undisclosed / other

Runway

Not public

No public cash ledger

Research

2 outputs

Commercial platform

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

13

linked evidence records

Autonomy

3

Execution

3

Verification

2

Scientific evidence

3

Capital

2

Traction

3
ReasonExecuteDataVerifyChemistryDrug discoveryMedicinal chemistry

41

Company

Generare

Series A · Europe · Paris, France · Founded 2023 · Updated 2026-04

Public deployment2Commercial data-generation platformCommercial partnership

Techbio company decoding microbial genomes to express silent chemistry and generate proprietary novel small-molecule data for drug discovery.

Capital

€25M

Series A · Apr 2026

Runway

Not public

No public cash ledger

Research

1 output

Commercial data-generation platform

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

2

Execution

3

Verification

2

Scientific evidence

3

Capital

3

Traction

3
DataExecuteReasonNatural productsDrug discoverySynthetic biology

42

Academic platform

RoboChem-Flex

Peer-reviewed prototype · Europe · Netherlands · Founded 2026 · Updated 2026-04

Published results1Peer-reviewed prototypeOpen research

Academic low-cost modular self-driving laboratory for automated chemical reaction optimization, with Python control software and Bayesian optimization.

Capital

Academic research

Undisclosed / other

Runway

Not public

No public cash ledger

Research

1 output

Peer-reviewed prototype

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

9

linked evidence records

Autonomy

3

Execution

3

Verification

3

Scientific evidence

4

Capital

1

Traction

2
ExecuteReasonInfrastructureVerifyChemistryLab automationOptimization

43

Platform initiative

Microsoft Discovery

Generally available · North America · Redmond, WA · Founded 2025 · Updated 2026-04

Public deployment5Commercial deploymentGenerally available enterprise platform; desktop app in preview

Microsoft's enterprise agentic R&D platform for hypothesis generation, simulation, analysis, and iterative experimentation across life sciences, materials, semiconductors, and engineering workflows.

Capital

Microsoft-funded platform

Undisclosed / other

Runway

Not public

No public cash ledger

Research

0 outputs

Commercial deployment

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

13

linked evidence records

Autonomy

3

Execution

2

Verification

3

Scientific evidence

2

Capital

4

Traction

2
ReasonExecuteVerifyDataInfrastructureBiologyChemistryMaterialsSemiconductors

44

Company

Cenevo

Commercial · North America / Europe · United States / United Kingdom · Founded 2025 rebrand · Updated 2026-02

Public deployment2CommercialProprietary

Lab orchestration and informatics platform formed from Labguru and Titian Software. Provides ELN/LIMS, sample management, workflow automation, protocol conversion, and AI agents for regulated labs.

Capital

Private

Undisclosed / other

Runway

Not public

No public cash ledger

Research

0 outputs

Commercial

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

9

linked evidence records

Autonomy

2

Execution

3

Verification

2

Scientific evidence

2

Capital

2

Traction

4
ExecuteDataInfrastructureBiologyLab automationScientific informatics

45

Company

Strateos

Commercial · North America · San Diego, CA · Founded 2012 · Updated 2026-05

Public deployment1CommercialProprietary

Robotic cloud lab for life sciences. Automated workflows for drug discovery, synthesis, and assays, accessible via API.

Capital

$56M

<$100M

Runway

Not public

No public cash ledger

Research

1 output

Commercial

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

2

Execution

4

Verification

2

Scientific evidence

2

Capital

2

Traction

3
ExecuteInfrastructureDataBiologyChemistryCloud lab

46

Company

Atinary

Commercial · Europe · Lausanne, Switzerland · Founded 2019 · Updated 2026-02

Public deployment5Commercial hardware and softwareProprietary

Self-driving lab orchestration and execution layer. Runs SDLabs software plus physical Scientific Discovery Factories for chemistry, materials, and pharma R&D teams.

Capital

Undisclosed

Undisclosed / other

Runway

Not public

No public cash ledger

Research

1 output

Commercial hardware and software

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

13

linked evidence records

Autonomy

3

Execution

3

Verification

3

Scientific evidence

3

Capital

1

Traction

2
ReasonExecuteVerifyDataChemistryMaterialsDrug discovery

47

Company

Fathom Therapeutics

Series A · North America · New York, NY · Founded 2023 · Updated 2026-05

Working prototype4Working prototypeProprietary

Physics- and AI-driven small-molecule drug design company formerly known as Atommap. Microcosmos simulates protein motion and interactions at atomic resolution to guide lab-in-the-loop discovery.

Capital

$47M

Series A · Apr 2026

Runway

Not public

No public cash ledger

Research

1 output

Working prototype

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

12

linked evidence records

Autonomy

2

Execution

2

Verification

2

Scientific evidence

3

Capital

3

Traction

3
ReasonExecuteDataVerifyDrug discoveryChemistryBiology

48

Company

Synthace

Growth · Europe · London, UK · Founded 2011 · Updated 2026-05

Public deployment3CommercialProprietary

Cloud experiment-design platform for biological R&D. Turns multivariate experiment designs into automation instructions and structured data that can be analyzed and reused.

Capital

$35M

Series C · Nov 2021

Runway

Not public

No public cash ledger

Research

1 output

Commercial

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

11

linked evidence records

Autonomy

2

Execution

3

Verification

2

Scientific evidence

2

Capital

3

Traction

3
ReasonExecuteDataBiologyExperiment designLab automation

49

Company

TetraScience

Growth · North America · Boston, MA · Founded 2014 · Updated 2026-05

Public deployment5CommercialProprietary

Scientific Data and AI Cloud for life sciences R&D. Replatforms raw instrument and experiment data into engineered, compliant datasets for analytics, automation, and scientific AI.

Capital

$80M

Series B · Apr 2021

Runway

Not public

No public cash ledger

Research

1 output

Commercial

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

1 deal

HighRes Biosolutions

Sources

12

linked evidence records

Autonomy

2

Execution

1

Verification

3

Scientific evidence

2

Capital

3

Traction

4
DataInfrastructureVerifyScientific dataBiopharmaLab automation

50

Company

Causaly

Growth · Europe · London, UK; San Francisco, CA · Founded 2018 · Updated 2026-05

Public deployment5Commercial platformProprietary

Agentic AI platform for life-sciences R&D. Combines biomedical knowledge graphs, scientific retrieval, and governed agents for target identification, biomarker research, evidence review, and portfolio decisions.

Capital

$60M

Series B · Jul 2023

Runway

Not public

No public cash ledger

Research

1 output

Commercial platform

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

13

linked evidence records

Autonomy

3

Execution

0

Verification

3

Scientific evidence

2

Capital

3

Traction

4
ReasonVerifyDataBiomedical researchDrug discoveryEvidence synthesis

51

Government initiative

Materials Genome Initiative

Policy and research network · North America · United States · Founded 2011 · Updated 2026-05

Working prototype2Government initiativePublic infrastructure

US federal multi-agency initiative for accelerated materials discovery and deployment. Coordinates infrastructure, data, autonomous experimentation, and policy for materials innovation.

Capital

Government program

Undisclosed / other

Runway

Not public

No public cash ledger

Research

1 output

Government initiative

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

1

Execution

1

Verification

3

Scientific evidence

4

Capital

2

Traction

4
InfrastructureDataVerifyMaterialsManufacturingPolicyData infrastructure

52

Company

Alloy Therapeutics

Growth · North America · Boston, MA · Founded 2017 · Updated 2026-04

Public deployment2Commercial infrastructureCommercial partnership

Tech-enabled biotech infrastructure and integrated services platform for biologics discovery and development, combining AI, real-world data, and wet-lab execution.

Capital

$40M

Series E · Apr 2026

Runway

Not public

No public cash ledger

Research

0 outputs

Commercial infrastructure

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

1

Execution

3

Verification

2

Scientific evidence

2

Capital

3

Traction

4
ExecuteDataInfrastructureBiologicsDrug discoveryBiotech infrastructure

53

Platform initiative

Amazon Bio Discovery

Commercial early access · North America · Seattle, WA · Founded 2026 · Updated 2026-04

Public deployment7Commercial productCommercial early-access plans, free trial, and free non-commercial academic tier

AWS's agentic application for lab-in-the-loop drug discovery, launched April 14, 2026 and available with a free trial and paid early-access plans. It exposes 40+ biology AI models, supports custom models, and connects computational workflows to CRO and wet-lab partners.

Capital

Amazon-funded service

Undisclosed / other

Runway

Not public

No public cash ledger

Research

0 outputs

Commercial product

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

15

linked evidence records

Autonomy

3

Execution

2

Verification

2

Scientific evidence

2

Capital

4

Traction

2
ReasonExecuteDataInfrastructureBiologyDrug discovery

54

Company

Autoscience Institute

Seed · North America · San Francisco, CA · Founded 2023 · Updated 2026-05

Published results3Peer-reviewed demoProprietary

Autonomous agents for ML research. Carl ideates and writes papers; Mira embeds new research directly into production ML models.

Capital

$14M

Seed · Mar 2026

Runway

Not public

No public cash ledger

Research

2 outputs

Peer-reviewed demo

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

11

linked evidence records

Autonomy

4

Execution

1

Verification

2

Scientific evidence

3

Capital

2

Traction

2
ReasonVerifyML research

55

Company

Radical AI

Seed · North America · New York, NY · Founded 2022 · Updated 2026-05

Published results2Open researchHybrid

AI platform for materials discovery. Focus on industrial biomanufacturing and novel functional materials.

Capital

$13.5M

<$100M

Runway

Not public

No public cash ledger

Research

1 output

Open research

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

3

Execution

3

Verification

2

Scientific evidence

2

Capital

2

Traction

2
ReasonExecuteDataMaterialsSimulation

56

Company

Helical

Seed · Europe · London, UK · Founded 2024 · Updated 2026-05

Public deployment4Production deploymentProprietary

Virtual AI lab for pharma R&D. Converts biological foundation models into reproducible in-silico discovery workflows for target identification, biomarker discovery, and therapeutic design.

Capital

$10M

Seed · Apr 2026

Runway

Not public

No public cash ledger

Research

1 output

Production deployment

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

12

linked evidence records

Autonomy

3

Execution

1

Verification

3

Scientific evidence

2

Capital

2

Traction

3
ReasonDataVerifyBiologyDrug discoveryBiomarkers

57

Company

Kebotix

Commercial · North America · Cambridge, MA · Founded 2017 · Updated 2026-05

Public deployment2Commercial platformProprietary

Self-driving laboratory company for chemicals and materials discovery. Combines AI planning, robotics, and high-throughput experimentation to shorten materials and molecule optimization loops.

Capital

$11M

Series A · Apr 2020

Runway

Not public

No public cash ledger

Research

1 output

Commercial platform

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

3

Execution

3

Verification

2

Scientific evidence

2

Capital

2

Traction

2
ReasonExecuteDataMaterialsChemistryGreen chemistry

58

Company

Artificial

Series A · North America · Palo Alto, CA · Founded 2019 · Updated 2026-05

Public deployment2Commercial platformProprietary

Lab orchestration software for life sciences R&D. Connects wet-lab instruments, informatics systems, scheduling, digital twins, and AI agents into controlled scientific workflows.

Capital

$22M

Series A · May 2021

Runway

Not public

No public cash ledger

Research

1 output

Commercial platform

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

9

linked evidence records

Autonomy

3

Execution

3

Verification

2

Scientific evidence

2

Capital

2

Traction

2
ExecuteInfrastructureDataLab automationBiologySynthetic biology

59

Company

Cellarity

Private scaleup · North America · Somerville, MA · Founded 2017 · Updated 2025-10

Working prototype6Platform pipelineProprietary

Flagship Pioneering company developing cell-state-correcting medicines. Uses single-cell technologies, network biology, and machine learning to map disease cell behavior and design interventions.

Capital

$121M

Series C · Oct 2022

Runway

Not public

No public cash ledger

Research

2 outputs

Platform pipeline

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

1 deal

Novo Nordisk

Sources

14

linked evidence records

Autonomy

2

Execution

2

Verification

3

Scientific evidence

2

Capital

3

Traction

2
ReasonDataVerifyBiologyDrug discoverySingle-cell biology

60

Company

Converge Bio

Series A · North America / Middle East · Boston, MA / Tel Aviv, Israel · Founded 2024 · Updated 2026-01

Public deployment2Commercial tractionCommercial partnership

Generative AI platform for drug discovery and development, spanning target discovery, antibody design, and protein manufacturing optimization.

Capital

$25M

Series A · Jan 2026

Runway

Not public

No public cash ledger

Research

0 outputs

Commercial traction

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

2

Execution

1

Verification

2

Scientific evidence

2

Capital

3

Traction

3
ReasonDataVerifyBiologyDrug discoveryProtein engineering

61

Company / product line

Riffyn

Commercial · North America · Oakland, CA · Founded 2014 · Updated 2026-05

Public deployment2CommercialProprietary

Scientific process design and data platform now offered as Riffyn X inside Siemens. Captures experimental methods, sample lineage, and process data in forms ready for analysis and machine learning.

Capital

$15M

Series B · May 2019

Runway

Not public

No public cash ledger

Research

1 output

Commercial

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

1

Execution

1

Verification

3

Scientific evidence

2

Capital

2

Traction

3
DataVerifyInfrastructureBioprocessingScientific dataExperiment design

62

Company

10x Science

Seed · North America · San Francisco, CA · Founded 2025 · Updated 2026-05

Working prototype5Announced platformProprietary

AI-native platform for next-generation protein characterization. Automates mass-spectrometry interpretation so biologic drug candidates can be characterized and quality-assessed faster.

Capital

$5M

Seed · Apr 2026

Runway

Not public

No public cash ledger

Research

1 output

Announced platform

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

14

linked evidence records

Autonomy

2

Execution

1

Verification

3

Scientific evidence

2

Capital

1

Traction

2
DataVerifyBiologyDrug discoveryProtein characterization

63

Company

Thesis

Seed · North America · San Francisco, CA · Founded 2025 · Updated 2026-05

Published results2Benchmark resultProprietary

Applied research lab automating parts of the ML research workflow — experiment planning, training, evaluation, iteration.

Capital

~$3M

<$100M

Runway

Not public

No public cash ledger

Research

1 output

Benchmark result

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

3

Execution

1

Verification

2

Scientific evidence

2

Capital

1

Traction

1
ReasonVerifyML research

64

Frontier AI lab

AMI Labs

Seed · Europe · Paris, France · Founded 2025 · Updated 2026-05

Working prototype2Announced labProprietary

Advanced Machine Intelligence — Yann LeCun's new lab. Building world models based on Joint Embedding Predictive Architecture (JEPA) rather than next-token LLMs; aims to learn from physical reality as the path to human-level intelligence.

Capital

$1.0B

Seed · Mar 2026

Runway

Not public

No public cash ledger

Research

1 output

Announced lab

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

2

Execution

1

Verification

1

Scientific evidence

1

Capital

4

Traction

1
ReasonDataWorld modelsGeneral intelligencePhysical reasoning

65

Company

Scivity Labs

Pre-seed · Europe · Yerevan, Armenia · Founded 2025 · Updated 2026-03

Working prototype2Self-reported platformProprietary

Autonomous science platform focused on computational research workflows that design, execute, and verify scientific work end-to-end, with public emphasis on validation outcomes and evidence surfaces.

Capital

Pre-seed, undisclosed

Undisclosed / other

Runway

Not public

No public cash ledger

Research

0 outputs

Self-reported platform

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

10

linked evidence records

Autonomy

3

Execution

2

Verification

2

Conservative score: public materials describe validation outcomes while thresholds, calibration, and check-composition logic remain private.

Scientific evidence

1

Capital

1

Traction

1
ReasonExecuteVerifyInfrastructureML researchBiologyChemistryGeneral science

66

Company

Tetsuwan Scientific

Pre-seed · North America · San Francisco, CA · Founded 2023 · Updated 2024-11

Working prototype4PilotProprietary

Execution-layer startup building ResearchOS and a future cloud lab so researchers or AI agents can translate natural-language procedures into machine-ready wet-lab workflows.

Capital

$3M

Pre-seed · Apr 2024

Runway

Not public

No public cash ledger

Research

0 outputs

Pilot

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

12

linked evidence records

Autonomy

2

Execution

3

Verification

1

Scientific evidence

1

Capital

1

Traction

2
ReasonExecuteInfrastructureBiologyLab automationCloud lab

67

Company

Zeon Systems

Seed · North America · San Francisco, CA · Founded 2025 · Updated 2026-05

Working prototype2PilotProprietary

Natural-language-to-robot-arm layer for lab automation. Scientists type protocols in English; software programs off-the-shelf robotics to execute them.

Capital

$0.5M

<$100M

Runway

Not public

No public cash ledger

Research

1 output

Pilot

Clinical

0 trials

No registry link

Non-dilutive

0 awards

No tracked grants

Deals

0 deals

No tracked partnerships

Sources

9

linked evidence records

Autonomy

2

Execution

3

Verification

1

Scientific evidence

1

Capital

1

Traction

1
ExecuteInfrastructureLab automationBiology

Timeline

Capital, claims,
and corrections.

The timeline combines company milestones, field-wide events, and ecosystem capital signals. Cross-market events stay separate from company funding so charts and foreign keys remain clean.

Apr 2026Featured

DOE ARPA-E CATALCHEM-E awards $34M to 12 AI + self-driving lab projects

First large federal bet explicitly tying autonomous labs to industrial catalyst development. Targets compressing catalyst discovery from ~10 years to ~1 year across universities and national labs.

Apr 2026Featured

OpenAI launches GPT-Rosalind for life sciences research

OpenAI introduced GPT-Rosalind on April 16, a frontier reasoning model tuned for biology, drug discovery, and translational medicine, alongside a Codex life-sciences plugin connecting to 50+ scientific tools. Available as a research preview through OpenAI's trusted access program with Amgen, Moderna, Thermo Fisher, and the Allen Institute as launch partners.

Feb 2026Featured

GPT-5 drives 36,000 CFPS experiments in Ginkgo Cloud Lab

OpenAI and Ginkgo reported a closed-loop autonomous CFPS optimization study on February 5: GPT-5 designed experiments, Ginkgo's Cloud Lab executed them with minimal human intervention, results returned to GPT-5, and the next round was proposed by the model. The campaign covered 36,000+ unique reaction compositions across 580 automated plates, six closed-loop rounds, about 40% lower sfGFP production cost, and a 27% titer increase.

Feb 2026Featured

Atinary opens Boston self-driving lab

Atinary announced its Boston AI-powered lab with two autonomous Scientific Discovery Factories running closed-loop Design-Make-Test-Analyze-Learn cycles. The lab integrates Atinary's no-code AI platform with robotics and instruments from ABB, Agilent, Bruker, Chemspeed, and Mettler-Toledo for small-molecule synthesis and catalysis.

May 2026

Milestone

Recursion Q1 2026: REC-4881 establishes clinical proof of concept in FAP

Recursion's Q1 2026 results, reported May 6, established clinical proof of concept for REC-4881 in familial adenomatous polyposis with significant precancerous polyp reduction; Recursion has initiated FDA engagement for a potential registrational study. The company also booked a fifth Sanofi milestone payment on a partnered first-in-class oncology program and reaffirmed runway into early 2028.

May 2026

Milestone

Ginkgo positions Nebula as its autonomous-lab core

Ginkgo's Q1 2026 results, reported May 7, highlighted Cloud Lab adoption from ProQR and Amazon's Bio Discovery platform. Jason Kelly positioned Nebula as the world's largest autonomous lab and targeted doubling the Nebula footprint in 2026. Q1 revenue was $19M with $373M in cash, cash equivalents and marketable securities.

May 2026

Milestone

Edison Scientific publishes LABBench2 biology research benchmark

Edison Scientific released LABBench2 on May 2, a 1,892-task benchmark spanning literature, databases, sequences, protocols, patents, trials, and source quality across 11 task families. Moves agent evaluation from short-form biology recall toward practical research workflows including retrieval, file handling, and tool use.

May 2026

Milestone

Eli Lilly / Profluent strike $2.25B AI recombinase pact

Eli Lilly and Profluent announced a multi-program strategic research collaboration to design and commercialize custom site-specific recombinases for severe-unmet-need diseases. Deal carries an upfront payment, committed R&D funding, up to $2.25B in development and commercial milestones, and tiered royalties on net sales.

Apr 2026

Company funding

Helical: $10M Seed

Seed round for a virtual AI lab that turns biological foundation models into reproducible in-silico pharma R&D workflows.

Apr 2026

Company funding

10x Science: $4.8M Seed

Seed round to build AI-native protein characterization for the verification bottleneck in biologic drug development.

Apr 2026

Ecosystem event

DOE ARPA-E CATALCHEM-E: Government grants · $34M

12 projects pairing AI with self-driving labs to compress catalyst-development timelines from ~10 years to ~1 year. Recipients include NC State ($2.99M), UW-Madison ($2.84M), Ames National Lab ($2.52M).

Apr 2026

Ecosystem event

Anthropic / Coefficient Bio: Acquisition · ~$400M

All-stock. First Anthropic M&A into a new domain. ~10 employees, ~$40M+ per employee. Stanton + Frey (ex-Prescient Design). Dimension VC reportedly 38,513% IRR.

Apr 2026

Ecosystem event

ProQR / Ginkgo Bioworks: Partnership · undisclosed

ProQR gained access to Ginkgo's Nebula autonomous lab for high-throughput data generation supporting Axiomer RNA-editing discovery. Ginkgo also made a strategic equity investment in ProQR.

Apr 2026

Ecosystem event

ARIA Activation Partners: Government program · 100M GBP (~$125M) open call

ARIA opened a 100M GBP call for 8-10 Activation Partners, explicitly adding AI-for-science tools, AI Scientist systems, and autonomous labs as capabilities to bring into ARIA-funded R&D. Open call ceiling, not yet committed awards — excluded from capital totals.

Apr 2026

Ecosystem event

Project Prometheus: physical-AI capital signal · $10B (adjacent, physical-AI)

Bloomberg-cited reporting said Project Prometheus closed a roughly $10B round at about a $38B valuation for a physical-AI lab focused on engineering and manufacturing physical products. Tracked as an adjacent ecosystem signal for context, not autonomous-science capital — excluded from capital totals.

Apr 2026

Milestone

Anthropic acquires Coefficient Bio

All-stock, ~$400M. First Anthropic M&A into a new domain. Signals that frontier labs will enter AI-for-science domain-by-domain through acqui-hires.

Apr 2026

Milestone

OpenAI publishes Industrial Policy paper

Calls for 'distributed AI-enabled laboratories' as public infrastructure. Commits $100K grants + $1M API credits, not capital to build the network.

Apr 2026

Milestone

DOE ARPA-E CATALCHEM-E awards $34M to 12 AI + self-driving lab projects

First large federal bet explicitly tying autonomous labs to industrial catalyst development. Targets compressing catalyst discovery from ~10 years to ~1 year across universities and national labs.

Apr 2026

Milestone

Sakana AI launches Marlin closed beta

First commercial product from Sakana. Autonomous enterprise research agent (Adaptive Branching MCTS + AI Scientist workflow) producing slide decks and long-form reports in a single extended run — the AI Scientist architecture repurposed for corporate strategy.

Apr 2026

Milestone

Chemify publishes three chemputation validation papers

Cronin/Chemify published three peer-reviewed papers in PNAS and Nature Communications sister journals validating the chemputer for autonomous drug synthesis and kinase inhibitor discovery.

Apr 2026

Milestone

Stanford AI Index 2026: AI agents trail PhD scientists on complex tasks

Stanford HAI's 2026 AI Index Report (released April 13) found that the best frontier AI agents score roughly half as well as human PhDs on complex multi-step scientific workflows, even as models passed the PhD-expert baseline on GPQA. A Nature commentary framed it as the field's first quantitative reality check on autonomous-science agents.

Apr 2026

Milestone

FutureHouse introduces DISCO enzyme design model

FutureHouse, Caltech, Mila, and collaborators introduced DISCO, a multimodal generative model that co-designs protein sequence and structure. The team reported functional new-to-nature carbene-transfer enzymes, including a B-H insertion design reaching 98% product and 5,170 total turnovers.

Apr 2026

Milestone

Sakana AI opens Fugu multi-agent beta

Sakana AI introduced Fugu, a multi-agent orchestration system that learns to route work across frontier foundation models and itself. Sakana frames the beta as an API product for coding, mathematics, and scientific-reasoning workloads.

Apr 2026

Milestone

Agent4Science launches as agents-only research social network

University of Chicago's Chenhao Tan launched Agent4Science, a Reddit-style site where AI agents share, debate, and review papers — including AI-generated ones — while humans can only observe. An early experiment in agent-to-agent scientific discourse described in Nature on April 20.

Apr 2026

Milestone

Isomorphic Labs publicly preparing first-in-human AI-designed drug trials

Speaking at WIRED Health on April 16, Isomorphic Labs president Max Jaderberg confirmed the AlphaFold-derived oncology pipeline is gearing up to enter the clinic, the first major operational signal that an AI-native drug-discovery program is reaching first-in-human studies.

Apr 2026

Milestone

OpenAI launches GPT-Rosalind for life sciences research

OpenAI introduced GPT-Rosalind on April 16, a frontier reasoning model tuned for biology, drug discovery, and translational medicine, alongside a Codex life-sciences plugin connecting to 50+ scientific tools. Available as a research preview through OpenAI's trusted access program with Amgen, Moderna, Thermo Fisher, and the Allen Institute as launch partners.

Apr 2026

Milestone

Google DeepMind launches Deep Research and Deep Research Max

Google DeepMind released Deep Research and Deep Research Max in public preview on April 21, autonomous research agents built on Gemini 3.1 Pro that combine open-web search with private data via Model Context Protocol. Deep Research Max runs roughly 160 search queries per task, targeting long-horizon research workflows.

Apr 2026

Milestone

OpenAI releases GeneBench scientific-agent benchmark

OpenAI released GeneBench on April 23, a benchmark of 103 multi-stage scientific data analysis tasks across 10 genomics and quantitative biology domains. Frontier models score around 25-33%, with OpenAI noting that individual tasks often correspond to multi-day projects for expert computational biologists.

Apr 2026

Milestone

Ginkgo closes Biosecurity divestiture to Tower Biosecurity

On April 3, 2026, Ginkgo completed the divestiture of substantially all Biosecurity-segment operations to Tower Biosecurity, also known as Perimeter Systems, receiving common stock representing about 20% of the purchaser on a fully diluted basis and refocusing the company around autonomous labs.

Apr 2026

Milestone

MGI releases autonomous experimentation materials R&D report

The Materials Genome Initiative published an autonomous experimentation report summarizing AMII workshop findings and next steps for accelerated materials R&D.

Apr 2026

Milestone

Ai2 updates AstaBench scientific-agent leaderboard

Ai2's spring 2026 AstaBench update reported new frontier-model results on a suite of 2,400+ scientific research problems spanning literature understanding, coding and execution, data analysis, and end-to-end discovery.

Apr 2026

Milestone

RoboChem-Flex publishes affordable modular self-driving lab

Nature Synthesis published RoboChem-Flex, a low-cost modular self-driving laboratory for autonomous reaction optimization with Python software, Bayesian optimization, closed-loop and human-in-the-loop modes, and six validation case studies.

Apr 2026

Milestone

Generare raises €20M Series A for microbial chemistry platform

Generare raised a €20M Series A co-led by Alven and Daphni to scale its platform for reading microbial genomes, expressing silent chemistry, and generating proprietary novel small-molecule data.

Apr 2026

Milestone

Alloy Therapeutics raises $40M Series E at $1B valuation

Alloy raised a $40M Series E at a $1B valuation, reporting 200+ partners, 100+ licensed therapeutic programs, 22 clinical programs, and positioning its AI, real-world-data, and wet-lab capabilities as on-demand biotech infrastructure.

Apr 2026

Milestone

Microsoft expands Discovery preview with enterprise R&D partners

Microsoft expanded preview access for Discovery, adding partner integrations, customer examples, and explicit interoperability with physical labs, robotics, and HPC-backed R&D workflows.

Apr 2026

Milestone

Anthropic releases BioMysteryBench for bioinformatics research

Anthropic introduced BioMysteryBench, a 99-task bioinformatics evaluation with expert baselines and reliability analysis, alongside Claude evaluations on the dataset.

Apr 2026

Milestone

AWS launches Amazon Bio Discovery agentic drug-research platform

AWS announced Amazon Bio Discovery on April 28: agentic AI on Bedrock that selects from 40+ biology foundation models, routes candidates to integrated CRO and cloud-lab partners (Ginkgo Nebula, Twist Bioscience, A-Alpha Bio anticipated) for synthesis and testing, and returns results into a lab-in-the-loop cycle. Early Memorial Sloan Kettering project triaged 300,000 antibody candidates in weeks.

Mar 2026

Company funding

Autoscience Institute: $14M Seed

Toyota Ventures, Perplexity Fund, S32, MaC participated. Commercial launch of Carl and Mira agents.

Mar 2026

Company funding

AMI Labs: $1.03B Seed

Yann LeCun's new lab. $3.5B pre-money — the largest seed round in European tech history. Signal that frontier-lab veterans are entering the science-AI space outside the Big Tech umbrella.

Methodology

Comparable data,
without false precision.

The market map uses a global anchor set across thirteen layers. Inclusion requires a material role in AI compute, models, infrastructure, agents, applications, robotics, science, or governance and a current primary source.

The deeper scorecard below applies only to organizations that materially affect autonomous scientific discovery. General-market anchors are never assigned science-specific scores; the capability index above uses its own published six-dimension method.

Dimensional scoring

Autonomy

How much of the scientific workflow can run without human step-by-step operation.

Execution

Whether the system can touch the physical world, run labs, trigger assays, or operate production scientific workflows.

Verification

How directly the system can evaluate, reproduce, critique, or measure scientific claims.

Scientific evidence

Strength of public evidence: papers, clinical data, benchmark results, open artifacts, or deployed research outputs.

Capital

Scale of committed capital, strategic partnerships, public-market access, or institutional funding.

Traction

Commercial, institutional, research, or user adoption signals beyond a launch announcement.

Source policy

Every deep-profile entity, funding event, milestone, benchmark definition, and measured result carries source IDs. The validator also checks market-layer coverage, anchor URLs, review dates, AGI weights, score ranges, and unique signal IDs.

v1 is manually curated. Codex automations and recurring refresh flows are intentionally deferred until the data contract is stable.

Data and citation

Funding totals exclude valuation-only discussions and milestone-contingent “up to” amounts. Cross-market events are stored separately from company funding to keep company foreign keys clean.

This page is free to reuse under Creative Commons BY 4.0. Citation: Scivity Labs (2026), “AI Progress & Market Landscape,” scivity.org/landscape.

Full dataset: JSON · market CSV · science entity CSV. Table CSVs: funding · financials · research · benchmark results · deals · trials. Machine-readable summary for AI agents: llms.txt.

333 source records are currently tracked.

Last updated · August 8, 202626 benchmark/progress records36 measured benchmark resultsCC BY 4.0 citation-ready dataset